Dear Pedro, Carolina and FIS Colleagues,

Firstly I want to congratulate Pedro and team for new FIS web site!
It looks nice and I am sure it will be useful tool for all of us.

Secondly – what is Neuroinformation?  
>From point of view of General Information Theory, it is needed a Subject for 
>which the reflection became information after receiving the evidence what the 
>reflection reflects.
But what we have into the Subject?
Does he operate with information or only with signals and reflections? 
Who is/are internal Sub-Subject(s) and evidence(s)? 
After receiving answers to these questions we may create hypothesizes what is 

I have my own understanding but it will be more good to listen other opinions.

What has been investigated by Neuroscience till now?

Friendly regards

From: Carolina Isiegas 
Sent: Wednesday, December 03, 2014 2:46 PM
Subject: [Fis] Neuroinformation?

Dear list,

    I have been reading during the last year all these interesting exchanges. 
Some of them terrific discussions! Given my scientific backgound (Molecular 
Neuroscience), I would like to hear your point of view on the topic of 
neuroinformation, how information "exists" within the Central Nervous Systems. 
My task was experimental; I was interested in investigating the molecular 
mechanisms underlying learning and memory, specifically, the role of the 
cAMP-PKA-CREB signaling pathway in such brain functions (In Ted Abel´s Lab at 
the University of Pennsylvania, where I spent 7 years). I generated several 
genetically modified mice in which I could regulate the expression of this 
pathway in specific brain regions and in which I studied the effects of 
upregulation or downregulation at the synaptic and behavioral levels. However, 
I am conscious that the "information flow" within the mouse Nervous System is 
far more complex that in the "simple" pathway that I was, my 
concrete question for you "Fishers" or "Fisers", how should we contemplate the 
micro and macro structures of information within the neural realm? what is 

Best wishes,


Carolina Isiegas

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