Dear Pedro and colleagues,

2. Eigenvectors of communication. Taking the motif from Loet, and continuing with the above, could we say that the life cycle itself establishes the eigenvectors of communication? It is intriguing that maintenance, persistence, self-propagation are the essential motives of communication for whatever life entities (from bacteria to ourselves). With the complexity increase there appear new, more sophisticated directions, but the basic ones probably remain intact. What could be these essential directions of communication?
I am not so convinced that there is an a priori relation between life and communication. Communication is not alive. Non-living systems (e.g., computers, robots) also communicate. Perhaps, it matters for the communication whether the communicators are living systems; but this needs to be specified.

Communication studies is not biology. Perhaps, there is a specific biological communication as Maturana claims: when molecules are exchanged, one can expect life. Can one have life without communication? It seems to me that one can have communication without life. Communication would then be the broader category and life a special case.


3. About logics in the pre-science, Joseph is quite right demanding that discussion to accompany principles or basic problems. Actually principles, rules, theories, etc. are interconnected or should be by a logic (or several logics?) in order to give validity and coherence to the different combinations of elements. For instance, in the biomolecular realm there is a fascinating interplay of activation and inhibition among the participating molecular partners (enzymes and proteins) as active elements. I am not aware that classical ideas from Jacob (La Logique du vivant) have been sufficiently continued; it is not about Crick's Central Dogma but about the logic of pathways, circuits, modules, etc. Probably both Torday and Ji have their own ideas about that-- I would be curious to hear from them.

4. I loved Michel's response to Arturo's challenge. I think that the two "zeros" I mentioned days ago (the unsolved themes around the cycle and around the observer) imply both multidisciplinary thinking and philosophical speculation...

Best wishes--Pedro

Pedro C. Marijuán
Grupo de Bioinformación / Bioinformation Group
Instituto Aragonés de Ciencias de la Salud
Centro de Investigación Biomédica de Aragón (CIBA)
Avda. San Juan Bosco, 13, planta 0
50009 Zaragoza, Spain
Tfno. +34 976 71 3526 (& 6818)

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