-------- Mensaje reenviado --------
Asunto: Re: [Fis] Summing up: New Year Lecture
Fecha: Mon, 22 Jan 2018 07:02:42 -0800
De: JOHN TORDAY <jtor...@ucla.edu>
Para: Pedro C. Marijuan <pcmarijuan.i...@aragon.es>
Dear FISers, I greatly appreciate Pedro's comments regarding my New Year
Lecture. I fully agree with his comment " That life's physiology is
based on the conjunction of a few principles: neguentropy, chemiosmosis,
and homeostasis-homeorhesis" applies to non-living states too. I did not
intend to make that statement exclusive, and if it sounded like that
Pedro's clarification is important. In fact have just published a paper
entitled "Quantum Mechanics Predicts Evolutionary Biology" which is
predicated on the hypothesis that self-referential self-organization is
the result of the Singularity/Big Bang, Newton's Third Law of
Thermodynamics that every action has an equal and opposite reaction.
That idea would apply to both evolutionary biology and to balanced
chemical reactions alike. As for the question of the emergence of
self-referential consciousness 'right at the beginning', I am in favor
of that concept, as I have expressed it in a recent paper, entitled
"From Cholesterol to Consciousness" (see attached) so I look forward to
reading your comments about that idea as well, since it has the
potential to fully integrate physics and biology in my humble opinion.
On Mon, Jan 22, 2018 at 4:01 AM, Pedro C. Marijuan
<pcmarijuan.i...@aragon.es <mailto:pcmarijuan.i...@aragon.es>> wrote:
Going to the extreme, I think this year opening lecture can be
summarized in three contentious points.
1. That life's physiology is based on the conjunction of a few
principles: neguentropy, chemiosmosis, and homeostasis-homeorhesis.
2. That communication (cell signaling) is an essential factor in the
multicellular evolution towards complexity.
3. That epigenetic inheritance and the obligate recursion to the
unicellular state become the basis of a new evolutionary theory.
I disagree with point 1, as I think some nonliving states could also
be characterized by those principles (eg, chemical
cycles/hypercycles in marine vents, and other outcomes derived from
"energy flows"); besides, some previous "info stuff" has to be in
place. Then I completely agree with point 2, for signaling is not
just another characteristic of the cell, it is "the" eukaryotic
trait par excellence. And I am curious on how point 3 could be
further substantiated... In this respect I recommend the two papers
that Bill sent to the list a few weeks ago. Do we need to postulate
the emergence of a form of "self-referential cognition" right at the
All the best--Pedro
El 09/01/2018 a las 19:05, Bill escribió:
Dear Pedro and Colleagues,
I have been following the thread of comments with great interest,
all of which have all been occasioned by John Torday's profound
insights about the nature of evolutionary development in light of
the importance of cell-cell signaling and molecular biology. From
the comments, it is clear that there is a strong impulse to seek a
means of integrating the role of symbiogenesis, viruses and mobile
elements, multilevel selection, niche construction, genomic
plasticity into a common narrative with an informational
perspective at its foundation.
In the spirit of that line of discussion, I am offering two
links that discuss evolution as an biologic information management
system. Some of this work shares direct commonality with John's,
since he and I are frequent collaborators.
Both of these articles can be considered as complementary to
Pedro's very fine article, 'How prokaryotes ‘encode’ their
environment: Systemic tools for organizing the information flow',
which is in BioSystems.
I am grateful to John for inviting me to participate in the forum
and to Pedro for encouraging me to share these manuscripts.
William B. Miller, Jr., M.D.
Pedro C. Marijuán
Grupo de Bioinformación / Bioinformation Group
Instituto Aragonés de Ciencias de la Salud
Centro de Investigación Biomédica de Aragón (CIBA)
Avda. San Juan Bosco, 13, planta 0
50009 Zaragoza, Spain
Tfno.+34 976 71 3526 <tel:+34%20976%2071%2035%2026> (& 6818)
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