I've been banging my head on this one for a while and have been working without a debugger (painful). But now I really need it.
I think the issue appeared when I upgraded to flash 10. I also pulled down the flash 10 debugger. When I hit the debug option in flex, IE comes up with the application but my breakpoints never get hit. After a bunch of research I found someone mentioning about connecting to the debugger. So I right clicked the app in IE7 and went to debugging. I tried to connect manually and it says it cannot connect. I see there's a lot of posts about this on the internet but they are either unresolved, the fixes didn't work, or it doesn't apply to my scenario (I'm on Vista Business not MAC). Does anyone know what I'm running into here and how to fix it? Thanks Scott

