This is a known limitation of the search  and replace engine of PSPad -
multiline search is not really supported.
You can try an addon: phReplace - A Multiline Search / Replace for PSPad
http://forum.pspad.com/read.php?2,34061#msg-34061
(I haven't tested such huge replacements yet, but hopefully it can be done...)

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PSPad freeware editor http://www.pspad.com

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