It can be a little slow sometimes when there are almost no or very few line breaks in the file, and possibly real-time spell-check is enabled. I often edit a 4MB file with one word per line on a 2GHz machine, and it opens in hardly more than a second.
-- <http://forum.pspad.com/read.php?2,40978,40985> PSPad freeware editor http://www.pspad.com
