A possible cause might be that Vista uses something called roaming for some
files.

Basically, if means that (for security reasons) files are not located where you
think they are, but rather somewhere withing you /users/username/.../roaming/...
folder.
This enables "writing" onto sensitive folders (i.e. /program files) without
losing the capability to undo all changes.

It will also cause some programs to access files that are different than what
you meant. It's reasonable that in windows explorer you'll see the updated file,
but an FTP client will only see (and upload) an empty file.

Solution: tell the FTP file to access the roaming folder or move the files to an
independent location (e.g. C:/MYFILES)

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