It's strange. I have windows 7 x64. The only problem I found when I investigate
it was in Program settings / Registr file types.
This functionality doesn't work, due to change in Windows API. In previous
system empty default value was empty string, in Windows 7 is it question mark
'?'.

This will be fixed in new build.
But I have no problem to set PSpad as default for TXT.
You don't need to run PSPad as admin for it, enough is check TXT in program
settings / System integration.
Please note, this settings is for current user. If you will run PSpad as
administrator, you will do this settings for administrator, not for you.

Items, what needs administrator rights are marked in program settings with small
rectangles.

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Odpovedet emailem