Ok, I got it to work on my Vista32, multi-user enabled, not running as portable.
However: If I run PsPad with Admin-rights (under an otherwise restricted user
account) I experience the same problem again: Cannot add files by any other
method than directly from within a running PSPad.

In other words: Everything is fine now as long as I run PsPad with regular
(restricted) user rights. 
If I run it with admin-rights, my normal user-environment is not able to add
files to the running instance (started with admin rights)

PsPad resides under C:\Program Files
Its settings under User\AppData\Roaming

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<http://forum.pspad.com/read.php?2,57697,57838>
PSPad freeware editor http://www.pspad.com

Odpovedet emailem