I am afraid I don't understand. 
When you open PHP file, there is no syntax highlighted? In this case is possible
your file size exceeded limit for highlighting. Go to program settings / Direct
edit button.
Find and change value of HLUpToSize e.g. to 1000000 (size in bytes)

In case your file is highlighted with another highlighter, there can be several
reasons:
1. you changed highlighter and PSPad remember it. Change it back to PHP
2. file is highlighter with HTML multihighlighter
3. you assign PHP (or your file) extension to another highlighter. Look on
statusbar for syntax name. Go to highlighter settings, choose highlighter from
statusbar and remove extension on the second tab

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Odpovedet emailem