Try to install PSPad as portable version. Or do not install the normal version into C:\programs\ or C:\programs\ (x86). Install it into e.g. C:\tools\. PSPad needs to write to *.ini files it it's folder. Windows does not allow this in program folders.
Or run PSPad as administrator. Or go to settings system integration and set it to save in user profile folder. -- <http://forum.pspad.com/read.php?2,67314,67922> PSPad freeware editor http://www.pspad.com
