There is no line calculation, but PSPad contains Calculate Block function in the
menu Tools.
Select lines, containing numbers and call Calculate block

For the first example, you need to transform line:ยจ
05,06,08,09,10,11,12,19,22,25,33,37,41,42,44,56,65,71,72,75
to 
05+06+08+09+10+11+12+19+22+25+33+37+41+42+44+56+65+71+72+75

Select this line and put it into function Tools/Expression evaluator

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Odpovedet emailem