yes, you can remove the control.dat file and run autorecon2-cp and 
autorecon3. Should only take a couple of hours depending on your 
processor
On Thu, 1 Dec 2016, Rizvi, Batool wrote:

>
> Hi Bruce,
> Thanks so much for the feedback, that is very helpful. We'll try deleting the 
> control points then. Is there a quick way to rerun recon-all without having 
> it take up to 5-8 hours?
>
> Also, a separate question, when running autorecon, after edits to the white 
> matter and pial surfaces, should we run the command -autorecon2 -autorecon3, 
> or would that include too many steps? I read that it's recommended to run 
> from -autorecon2-cp instead?
>
>
> Thanks so much for your help,
> B
>
> ________________________________________
> From: freesurfer-boun...@nmr.mgh.harvard.edu 
> [freesurfer-boun...@nmr.mgh.harvard.edu] on behalf of Bruce Fischl 
> [fis...@nmr.mgh.harvard.edu]
> Sent: Thursday, December 01, 2016 4:04 PM
> To: Freesurfer support list
> Subject: Re: [Freesurfer] white matter segmentation incorrect after intensity 
> change
>
> the problme is that you have several control points in voxels that aren't
> entirely wm. For example, 129, 134, 173 is a control point and it has no wm
> in it. This causes the intensity in that region to go up way too high, as
> we will normalize the control points to the desired wm intensity (110). I
> ran it without any control points and it worked pretty well. You should
> probably get rid of your control.dat. If you think that those thin frontal
> strands should go out a bit further, since some voxels that are entirely
> white matter (e.g. 134, 135, 162) but have an intensity that is less than
> 110 (this one is 103 after normalizating) and it will bring the intensity
> up a bit in that entire region (by the ratio of 110/103).
>
> On Thu, 1 Dec 2016, Rizvi, Batool wrote:
>
>> Hi Bruce,
>> Thanks for your reply. It is actually brighter on the brainmask.mgz than the 
>> orig.mgz when I checked. I'm uploading the freesurfer subject here.
>>
>> Thanks!
>> BR
>>
>> ________________________________________
>> From: freesurfer-boun...@nmr.mgh.harvard.edu 
>> [freesurfer-boun...@nmr.mgh.harvard.edu] on behalf of Bruce Fischl 
>> [fis...@nmr.mgh.harvard.edu]
>> Sent: Thursday, December 01, 2016 2:31 PM
>> To: Freesurfer support list
>> Subject: Re: [Freesurfer] white matter segmentation incorrect after 
>> intensity change
>>
>> hmmm, that's awfully bright. Is it also bright on the orig.mgz? It's not
>> really possible to diagnose from a single slice from a single subject. If
>> you tar, gzip and upload the subject one of us will take a look
>>
>> cheers
>> Bruce
>> On Thu, 1
>> Dec 2016, Rizvi, Batool wrote:
>>
>>>
>>> Hi FreeSurfer experts,
>>>
>>>
>>>
>>> After running -autorecon2 and -autorecon3, we're seeing issues for some of
>>> the subjects, which now start showing changes in intensity/brightness in
>>> some voxels, and this increased intensity is now missed by the white matter
>>> and grey matter segmentation, and is labeled as non-brain matter.
>>>
>>>
>>>
>>>  Attached is an example of a subject's brain that was segmented incorrectly,
>>> which we think is due to the intensity around that frontal region. We hadn't
>>> added control points in that region, so we are unsure what the cause of the
>>> intensity change is. In our first pass before running -autorecon2
>>> -autorecon3, we did not notice this error or the intensity values to be so
>>> bright for that region.
>>>
>>>
>>>
>>> Thanks for your help!
>>>
>>> BR
>>>
>>>
>>>
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