sure, good luck
Bruce
On Thu, 1 Dec 2016, Rizvi, Batool wrote:

> Sounds great, thanks again for your help and will try out your 
> recommendations.
> Have a great day!
>
> B
>
> ________________________________________
> From: freesurfer-boun...@nmr.mgh.harvard.edu 
> [freesurfer-boun...@nmr.mgh.harvard.edu] on behalf of Bruce Fischl 
> [fis...@nmr.mgh.harvard.edu]
> Sent: Thursday, December 01, 2016 4:27 PM
> To: Freesurfer support list
> Subject: Re: [Freesurfer] white matter segmentation incorrect after intensity 
> change
>
> yes, you can remove the control.dat file and run autorecon2-cp and
> autorecon3. Should only take a couple of hours depending on your
> processor
> On Thu, 1 Dec 2016, Rizvi, Batool wrote:
>
>>
>> Hi Bruce,
>> Thanks so much for the feedback, that is very helpful. We'll try deleting 
>> the control points then. Is there a quick way to rerun recon-all without 
>> having it take up to 5-8 hours?
>>
>> Also, a separate question, when running autorecon, after edits to the white 
>> matter and pial surfaces, should we run the command -autorecon2 -autorecon3, 
>> or would that include too many steps? I read that it's recommended to run 
>> from -autorecon2-cp instead?
>>
>>
>> Thanks so much for your help,
>> B
>>
>> ________________________________________
>> From: freesurfer-boun...@nmr.mgh.harvard.edu 
>> [freesurfer-boun...@nmr.mgh.harvard.edu] on behalf of Bruce Fischl 
>> [fis...@nmr.mgh.harvard.edu]
>> Sent: Thursday, December 01, 2016 4:04 PM
>> To: Freesurfer support list
>> Subject: Re: [Freesurfer] white matter segmentation incorrect after 
>> intensity change
>>
>> the problme is that you have several control points in voxels that aren't
>> entirely wm. For example, 129, 134, 173 is a control point and it has no wm
>> in it. This causes the intensity in that region to go up way too high, as
>> we will normalize the control points to the desired wm intensity (110). I
>> ran it without any control points and it worked pretty well. You should
>> probably get rid of your control.dat. If you think that those thin frontal
>> strands should go out a bit further, since some voxels that are entirely
>> white matter (e.g. 134, 135, 162) but have an intensity that is less than
>> 110 (this one is 103 after normalizating) and it will bring the intensity
>> up a bit in that entire region (by the ratio of 110/103).
>>
>> On Thu, 1 Dec 2016, Rizvi, Batool wrote:
>>
>>> Hi Bruce,
>>> Thanks for your reply. It is actually brighter on the brainmask.mgz than 
>>> the orig.mgz when I checked. I'm uploading the freesurfer subject here.
>>>
>>> Thanks!
>>> BR
>>>
>>> ________________________________________
>>> From: freesurfer-boun...@nmr.mgh.harvard.edu 
>>> [freesurfer-boun...@nmr.mgh.harvard.edu] on behalf of Bruce Fischl 
>>> [fis...@nmr.mgh.harvard.edu]
>>> Sent: Thursday, December 01, 2016 2:31 PM
>>> To: Freesurfer support list
>>> Subject: Re: [Freesurfer] white matter segmentation incorrect after 
>>> intensity change
>>>
>>> hmmm, that's awfully bright. Is it also bright on the orig.mgz? It's not
>>> really possible to diagnose from a single slice from a single subject. If
>>> you tar, gzip and upload the subject one of us will take a look
>>>
>>> cheers
>>> Bruce
>>> On Thu, 1
>>> Dec 2016, Rizvi, Batool wrote:
>>>
>>>>
>>>> Hi FreeSurfer experts,
>>>>
>>>>
>>>>
>>>> After running -autorecon2 and -autorecon3, we're seeing issues for some of
>>>> the subjects, which now start showing changes in intensity/brightness in
>>>> some voxels, and this increased intensity is now missed by the white matter
>>>> and grey matter segmentation, and is labeled as non-brain matter.
>>>>
>>>>
>>>>
>>>>  Attached is an example of a subject's brain that was segmented 
>>>> incorrectly,
>>>> which we think is due to the intensity around that frontal region. We 
>>>> hadn't
>>>> added control points in that region, so we are unsure what the cause of the
>>>> intensity change is. In our first pass before running -autorecon2
>>>> -autorecon3, we did not notice this error or the intensity values to be so
>>>> bright for that region.
>>>>
>>>>
>>>>
>>>> Thanks for your help!
>>>>
>>>> BR
>>>>
>>>>
>>>>
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