You will need to run gtmseg --s subject (takes an hour or so), then add 
--seg gtmseg.mgz to the cmd line


On 08/14/2017 04:12 PM, Shane Schofield wrote:
> Hi Dr  Greve,
>
> Are the settings correct to do partial volume correction of my MD images?
>
> mri_gtmpvc --i subject/dtrecon/adc.nii.gz --reg 
> subject/dtrecon/register.lta --psf 0 --seg subject/mri/gtmseg.mgz 
> --default-seg-merge --auto-mask PSF .01 --mgx 0.25 --o 
> subject/dtrecon/adc.pvc.mgz --no-rescale
>
> Thank you!
>
>
>
> On Monday, August 14, 2017, 4:36:28 PM GMT+1, Douglas N Greve 
> <gr...@nmr.mgh.harvard.edu> wrote:
>
>
> The mri_gtmpvc command will remove volume fraction effects. Look at the
> PETsurfer page. Run it with --psf 0 and use the muller-gartner output.
> The output will only be valid for gray matter
>
>
> On 08/12/2017 10:55 AM, Bruce Fischl wrote:
> > Hi Shane
> >
> > we do have some tools to deal with it like
> > mri_compute_volume_fractions and mri_compute_volume_intensities, or
> > maybe Doug's PET stuff. At the very least you should probably regress
> > thickness out.
> >
> > cheers
> > Bruce
> >
> > On Sat, 12 Aug 2017, Shane Schofield wrote:
> >
> >> Thank you both.
> >>
> >> How can I deal with partial volume in this case? Would it be possible
> >> to use
> >> the partial volume tool for PET on my MD volumes? Sorry if it is a 
> silly
> >> idea.
> >>
> >> Best Wishes,
> >> Shane
> >>
> >>
> >> On Friday, August 11, 2017, 6:19:45 PM GMT+1, Yendiki, Anastasia
> >> <ayend...@mgh.harvard.edu <mailto:ayend...@mgh.harvard.edu>> wrote:
> >>
> >>
> >> Agreed, especially so with MD. Keep in mind that you¹re upsampling MD
> >> from
> >> a lower-res (diffusion) space to a higher-res (T1) space, so it
> >> should be
> >> smooth already, relatively to measure derived from the T1. And MD 
> varies
> >> pretty smoothly (it¹s a mean of 3 things, after all).
> >>
> >> On 8/11/17, 1:11 PM, "Bruce Fischl" <fis...@nmr.mgh.harvard.edu 
> <mailto:fis...@nmr.mgh.harvard.edu>> wrote:
> >>
> >> >Hi Shane
> >> >
> >> >not really - it totally depends on the size of the effect you are
> >> looking
> >> >for. I would be *very* careful about partial volume effects though
> >> >
> >> >cheers
> >> >Bruce
> >> >On Fri,
> >> >11 Aug 2017, Shane Schofield wrote:
> >> >
> >> >> Appreciate it Dr Bruce. Do you have guidelines for smoothing MD?
> >> >>
> >> >> Dr Yendiki, I am trying to investigate whether cortical MD can be a
> >> >>marker
> >> >> of neurodegeneration. The idea is that during the early stages of a
> >> >>disease,
> >> >> cellular microstructure may breakdown before cortical thinning
> >> occurs.
> >> >>This
> >> >> results in "less" barriers against diffusion resulting in an
> >> increase of
> >> >> MD.
> >> >>
> >> >>
> >> >> On Friday, August 11, 2017, 5:49:40 PM GMT+1, Bruce Fischl
> >> >> <fis...@nmr.mgh.harvard.edu <mailto:fis...@nmr.mgh.harvard.edu>> 
> wrote:
> >> >>
> >> >>
> >> >> Hi Shane
> >> >>
> >> >> you probably don't need cvs as it is more to extend the 
> surface-based
> >> >> registration to the entire volume. Here you just need the
> >> surface-based
> >> >> registration I believe. Use mri_vol2surf to sample the FA onto the
> >> >>surface.
> >> >> After that it is identical to a thickness study
> >> >>
> >> >> cheers
> >> >> Bruce
> >> >>
> >> >>
> >> >>
> >> >> On Fri, 11 Aug 2017, Shane Schofield
> >> >> wrote:
> >> >>
> >> >> > Thanks Dr Yendiki.
> >> >> >
> >> >> > I am more interested to compare MD in grey matter regions by
> >> putting
> >> >>the
> >> >> MD on the surface, and then do a glmfit type of comparisons. Is
> >> that OK?
> >> >> Would you recommend me
> >> >> > to smooth the data after spatial normalisation? I have also used
> >> the
> >> >> mri_cvs_register as described on the tutorial.
> >> >> >
> >> >> >
> >> >> > On Friday, August 11, 2017, 7:03:49 AM GMT+1, Shane Schofield
> >> >> <shane.schofi...@yahoo.com <mailto:shane.schofi...@yahoo.com>> 
> wrote:
> >> >> >
> >> >> >
> >> >> > Hi DTI Experts,
> >> >> >
> >> >> > Is it sensible to do comparisons of MD on the cortex surface 
> like a
> >> >>normal
> >> >> cortical thickness comparisons between group? If the answer is
> >> yes, are
> >> >> there recommended on
> >> >> > smoothing ?
> >> >> >
> >> >> > DT_RECON has been completed in Freesurfer.
> >> >> >
> >> >> > Thank you.
> >> >> >
> >> >> >
> >> >> >
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> -- 
> Douglas N. Greve, Ph.D.
> MGH-NMR Center
> gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>
> Phone Number: 617-724-2358
> Fax: 617-726-7422
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Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358
Fax: 617-726-7422

Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
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