Yes, I think so

On 9/6/19 12:56 PM, Barletta, Valeria wrote:
> I did a correction for multiple comparison for every analysis... The 
> interaction survived.
> The interaction voxels do not overlap, apparently. So can I use doss 
> and consider my results ok?
> ------------------------------------------------------------------------
> *From:* freesurfer-boun...@nmr.mgh.harvard.edu 
> <freesurfer-boun...@nmr.mgh.harvard.edu> on behalf of Greve, Douglas 
> N.,Ph.D. <dgr...@mgh.harvard.edu>
> *Sent:* Friday, September 6, 2019 12:46 PM
> *To:* freesurfer@nmr.mgh.harvard.edu <freesurfer@nmr.mgh.harvard.edu>
> *Subject:* Re: [Freesurfer] Fw: question on GLM
> See whether the interaction survives correction for multiple 
> comparisons. If it does not, then proceed with doss. If it does not, 
> see whether the interaction voxels overlap with your contrast of 
> interest; if not, then proceed with doss.
>
> On 9/6/2019 11:28 AM, Barletta, Valeria wrote:
>> So when I use doss   (and the contrast  -1 +1 0), I have very similar 
>> results to those that I got when I completely remove age:
>>
>>
>> ------------------------------------------------------------------------
>> *From:* freesurfer-boun...@nmr.mgh.harvard.edu 
>> <mailto:freesurfer-boun...@nmr.mgh.harvard.edu> 
>> <freesurfer-boun...@nmr.mgh.harvard.edu> 
>> <mailto:freesurfer-boun...@nmr.mgh.harvard.edu> on behalf of Greve, 
>> Douglas N.,Ph.D. <dgr...@mgh.harvard.edu> <mailto:dgr...@mgh.harvard.edu>
>> *Sent:* Friday, September 6, 2019 10:38 AM
>> *To:* freesurfer@nmr.mgh.harvard.edu 
>> <mailto:freesurfer@nmr.mgh.harvard.edu> 
>> <freesurfer@nmr.mgh.harvard.edu> <mailto:freesurfer@nmr.mgh.harvard.edu>
>> *Subject:* Re: [Freesurfer] Fw: question on GLM
>> Did you try using DOSS?
>>
>> On 9/6/2019 9:51 AM, Barletta, Valeria wrote:
>>> Dear Doug,
>>> As you suggested yesterday, I launched the GLM to check for 
>>> interactions group-age with the contrast:
>>> 0 0 +1 -1
>>> And I obtained this image:
>>>
>>> Then I re-launched my model including age as a covariate and I 
>>> obtained very similar results:
>>>
>>>
>>> Finally, I re-launched the model excluding age and I obtained a very 
>>> different thing, which is actually more consistent with my data:
>>>
>>>
>>> How shall I interpret this? Shall I exclude age from my analysis? (I 
>>> do not really expect it to have an influence on my variable y)
>>>
>>> Thank you,
>>> Vale
>>> ------------------------------------------------------------------------
>>> *From:* freesurfer-boun...@nmr.mgh.harvard.edu 
>>> <mailto:freesurfer-boun...@nmr.mgh.harvard.edu> 
>>> <freesurfer-boun...@nmr.mgh.harvard.edu> 
>>> <mailto:freesurfer-boun...@nmr.mgh.harvard.edu> on behalf of Greve, 
>>> Douglas N.,Ph.D. <dgr...@mgh.harvard.edu> 
>>> <mailto:dgr...@mgh.harvard.edu>
>>> *Sent:* Wednesday, August 28, 2019 6:03 PM
>>> *To:* freesurfer@nmr.mgh.harvard.edu 
>>> <mailto:freesurfer@nmr.mgh.harvard.edu> 
>>> <freesurfer@nmr.mgh.harvard.edu> <mailto:freesurfer@nmr.mgh.harvard.edu>
>>> *Subject:* Re: [Freesurfer] Fw: question on GLM
>>> It is showing
>>> b = g2 - g1
>>> so negative means that g1 > g2
>>>
>>>
>>> On 8/28/19 1:59 PM, Barletta, Valeria wrote:
>>> >
>>> > Forgot to report my contrast matrix:
>>> >
>>> > -1 1 0 0
>>> >
>>> >
>>> > Thanks,
>>> > Valeria
>>> > 
>>> ------------------------------------------------------------------------
>>> > *From:* Barletta, Valeria
>>> > *Sent:* Wednesday, August 28, 2019 1:02 PM
>>> > *To:* Freesurfer support list <freesurfer@nmr.mgh.harvard.edu> 
>>> <mailto:freesurfer@nmr.mgh.harvard.edu>
>>> > *Subject:* question on GLM
>>> > Good afternoon!
>>> > I have a question on the Freesurfer GLM.
>>> > The command:
>>> >
>>> > mri_glmfit-sim --glmdir
>>> > ${glm_dir}/${hemi}_contrast-${contrast}_${surfname_cme} --cache 
>>> 1.3 neg
>>> >
>>> > is giving me blue clusters (see attached picture). Do blue clusters
>>> > mean that my variable y is LOWER in the FIRST or the SECOND group
>>> > listed in the FSGD file?
>>> >
>>> > Thanks,
>>> > Valeria
>>> >
>>> > _______________________________________________
>>> > Freesurfer mailing list
>>> > Freesurfer@nmr.mgh.harvard.edu <mailto:Freesurfer@nmr.mgh.harvard.edu>
>>> > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>>>
>>>
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>>
>>
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>
>
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