It sounds like it would be a one-group, two-variable situation, like this
https://surfer.nmr.mgh.harvard.edu/fswiki/Fsgdf1G2V
Is that not correct?


On 11/28/2019 5:24 AM, Ferraro, Pilar wrote:

        External Email - Use Caution

Hi,

I apologize if I did not explain my issue properly.
I'm interested in looking at age-related thickness reductions in 1 group 
(patients), but I'd like to also account for the effect of disease duration.
We can say that in my case disease duration is the nuisance factor.
Briefly, I have the same issue reported in here 
(https://www.mail-archive.com/freesurfer@nmr.mgh.harvard.edu/msg32860.html), 
but with only one group.
How would you recommend to proceed?

Many  thanks,

Pilar

________________________________
Message: 2
Date: Wed, 27 Nov 2019 16:56:20 +0000
From: "Greve, Douglas N.,Ph.D." 
<dgr...@mgh.harvard.edu><mailto:dgr...@mgh.harvard.edu>
Subject: Re: [Freesurfer] [External] Freesurfer Digest, Vol 189, Issue
        36
To: "freesurfer@nmr.mgh.harvard.edu"<mailto:freesurfer@nmr.mgh.harvard.edu> 
<freesurfer@nmr.mgh.harvard.edu><mailto:freesurfer@nmr.mgh.harvard.edu>
Message-ID: 
<fbb77a97-61b5-fac5-e2b3-0ee327e29...@mgh.harvard.edu><mailto:fbb77a97-61b5-fac5-e2b3-0ee327e29...@mgh.harvard.edu>
Content-Type: text/plain; charset="utf-8"

what is the difference between and independent variable and a covariate?

On 11/27/2019 6:57 AM, Ferraro, Pilar wrote:
>          External Email - Use Caution
>
> Yes, I did.
> But in this case I have two factors, not only one. In particular, I have an 
> independent variable X and a covariate I?d like to include in the model.
> How would you suggest to proceed?
>
>
> Thanks,
>
> Pilar



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