Could I revive within me Her symphony and song To such deep delight ’twould win me That with music loud and long I would build that pleasure dome in air That sunny dome, those caves of ice etc. etc.
> On Jul 21, 2021, at 8:41 AM, Frank Wimberly <[email protected]> wrote: > > When I was in the Robotics Institute (now department) at CMU, Raj Reddy used > to say that a professor would be easy to replace with an AI program. He felt > that a genuinely hard problem would be to develop an intelligent bulldozer. > That's why I have suggested to Stephen over the years that he build a > miniature bulldozer that could read a topographic map and create that > landscape on the sand table. > > The few people who don't know what I'm talking about should see simtable.com > <https://linkprotect.cudasvc.com/url?a=http%3a%2f%2fsimtable.com&c=E,1,RtDS8sTKXJpbu-QPY46tn5LYUPUIM42ANJRngp6qq1wPJewk7zevGDHXsPahW7S4qNHZ-cC08fmTsqXnDyBSUm_P979JBhy-z9PqjXHjEEl_KR6iR7D03Qw,&typo=1> > > Frank > > --- > Frank C. Wimberly > 140 Calle Ojo Feliz, > Santa Fe, NM 87505 > > 505 670-9918 > Santa Fe, NM > > On Tue, Jul 20, 2021, 5:14 PM Marcus Daniels <[email protected] > <mailto:[email protected]>> wrote: > I don’t have the quote handy but I recall the folks at Allen AI talking about > their hard problems. > > Acing the SAT, easy. Math is the hardest. > > > > From: Friam <[email protected] <mailto:[email protected]>> On > Behalf Of Patrick Reilly > Sent: Tuesday, July 20, 2021 3:02 PM > To: The Friday Morning Applied Complexity Coffee Group <[email protected] > <mailto:[email protected]>> > Subject: Re: [FRIAM] Can current AI beat humans at doing science? > > > > Prof. West has it right. Human intelligence requires melding intents. Solving > mathematical algorithms requires no creativity or shifting of intentions. > > On Tuesday, July 20, 2021, Prof David West <[email protected] > <mailto:[email protected]>> wrote: > > Thirty something years ago, Alan Newell walked into his classroom and > announced, "over Christmas break, Herb Simon and I created an artificial > intelligence." He was referring to the program Bacon, which fed with the same > dataset as the human deduced the same set of "laws." It even deduced a couple > of minor ones that Bacon missed (or, at least, did not publish). > > > > Simon and Newell tried to publish a paper with Bacon as author, but were > rejected. > > > > AlphaFold (which I think is based on a program Google announced but has yet > to publish in a "proper" journal) is, to me, akin to Bacon, in that it is not > "doing science," but is merely a tool that resolves a very specific > scientific problem and the use of that tool will facilitate humans who > actually do the science. > > > > I will change my mind when the journals of record publish a paper authored by > AlphaFold (or kin) as author and that paper at least posits a credible theory > or partial theory that transcends "here is the fold of the xyz sequence to > address why that fold is 'necessary' or 'useful'. > > > > davew > > > > > > On Tue, Jul 20, 2021, at 1:12 PM, Pieter Steenekamp wrote: > > A year or so ago, Deepmind's AlphGo defeated the then world Go-champion Lee > Sedol at a time when leading Ai researchers predicted it will be at least 10 > years before AI can reach that level. But the valid question then was - why > so excited? It's just a game. There is an interesting documentary on youtube > about this at https://www.youtube.com/watch?v=WXuK6gekU1Y > <https://www.youtube.com/watch?v=WXuK6gekU1Y> > > > What's happening now is that AI makes scientific discoveries beyond human > ability. > > > > Is anybody worried where it will end? > > > > I quote from https://www.nature.com/articles/s41586-021-03819-2 > <https://www.nature.com/articles/s41586-021-03819-2> > Highly accurate protein structure prediction with AlphaFold > > Proteins are essential to life, and understanding their structure can > facilitate a mechanistic understanding of their function. Through an enormous > experimental effort1–4, the structures of around 100,000 unique proteins have > been determined5, but this represents a small fraction of the billions of > known protein sequences6,7. Structural coverage is bottlenecked by the months > to years of painstaking effort required to determine a single protein > structure. Accurate computational approaches are needed to address this gap > and to enable large-scale structural bioinformatics. Predicting the 3-D > structure that a protein will adopt based solely on its amino acid sequence, > the structure prediction component of the ‘protein folding problem’8, has > been an important open research problem for more than 50 years9. Despite > recent progress10–14, existing methods fall far short of atomic accuracy, > especially when no homologous structure is available. Here we provide the > first computational method that can regularly predict protein structures with > atomic accuracy even where no similar structure is known. We validated an > entirely redesigned version of our neural network-based model, AlphaFold, in > the challenging 14th Critical Assessment of protein Structure Prediction > (CASP14)15, demonstrating accuracy competitive with experiment in a majority > of cases and greatly outperforming other methods. Underpinning the latest > version of AlphaFold is a novel machine learning approach that incorporates > physical and biological knowledge about protein structure, leveraging > multi-sequence alignments, into the design of the deep learning algorithm. > > > > > > > > > > - .... . -..-. . -. -.. -..-. .. ... -..-. .... . .-. . > > FRIAM Applied Complexity Group listserv > > Zoom Fridays 9:30a-12p Mtn GMT-6 bit.ly/virtualfriam > <https://linkprotect.cudasvc.com/url?a=http%3a%2f%2fbit.ly%2fvirtualfriam&c=E,1,i1Txu_Pbr-TXsfzehICF-41z5gsZ5-EJ6cwb0tRDbom9gWHK9Ct8Fj0kMJyKoXsP4B5B-X0ijBkBzMKQBtD4mCPLxzIPt2Zd7-Kw2kqD2U9VgNd-INU,&typo=1> > un/subscribe http://redfish.com/mailman/listinfo/friam_redfish.com > <https://linkprotect.cudasvc.com/url?a=http%3a%2f%2fredfish.com%2fmailman%2flistinfo%2ffriam_redfish.com&c=E,1,hoF2VXgt5nJTIk5tcnW5ryHnvUwNOAaxvpT0kcwFO3Eb1TaMicYuvKY6GoGZsPKZNqmGOPx13FI0-3gKvn4qx4uNUefqTiBEol_BLUHNS9Ui&typo=1> > FRIAM-COMIC http://friam-comic.blogspot.com/ > <https://linkprotect.cudasvc.com/url?a=http%3a%2f%2ffriam-comic.blogspot.com%2f&c=E,1,pWmQffZFTI8OYg2iR0YhRr9p0LubKtoRW2ND-_oB_ceYAuycjs7ATsj_U827gd91WMzqJTdEj2pxIzIU7nBDItQrP3t21Rpc7ajoXypNRkD0GTwtEO_5yi2iBQ2J&typo=1> > archives: http://friam.471366.n2.nabble.com/ > <http://friam.471366.n2.nabble.com/> > > > > > > > -- > Sent from Gmail Mobile > > - .... . -..-. . -. -.. -..-. .. ... -..-. .... . .-. . > FRIAM Applied Complexity Group listserv > Zoom Fridays 9:30a-12p Mtn GMT-6 bit.ly/virtualfriam > <https://linkprotect.cudasvc.com/url?a=http%3a%2f%2fbit.ly%2fvirtualfriam&c=E,1,VVzJ7f7sUYB-Z9gpIuUf2maeOj5uUDYf0b4TMrWIcHeXv_enV6-Bmuc5jOlQKZSIoEVEs9h-ZdqfZkNXmaY_5yPy8a3FIb00P9UrPLIeT8IAbIrgd8dqDw,,&typo=1> > un/subscribe http://redfish.com/mailman/listinfo/friam_redfish.com > <https://linkprotect.cudasvc.com/url?a=http%3a%2f%2fredfish.com%2fmailman%2flistinfo%2ffriam_redfish.com&c=E,1,NJDSpAuhszrbqr1OeMRj8z03b_LFCpVSJHNtHRCq6JGC__ZgObLfbzU9Cr-t0ppg5ILZwwPZZ_iwn96gpstx_v2_hKItGh6-A5Xep149tPP_JTcR&typo=1> > FRIAM-COMIC http://friam-comic.blogspot.com/ > <https://linkprotect.cudasvc.com/url?a=http%3a%2f%2ffriam-comic.blogspot.com%2f&c=E,1,_CEBHNSoVsnFX1uuOG9fRYyuIUvJAC9WIjKMq-21jb7atYE_hQL0pzXxdKPjP12e9eyBisEI4PXxyLTh9m2at16P9So0r7lHCw2wLSPZAOg,&typo=1> > archives: http://friam.471366.n2.nabble.com/ > <http://friam.471366.n2.nabble.com/> > - .... . -..-. . -. -.. -..-. .. ... -..-. .... . .-. . > FRIAM Applied Complexity Group listserv > Zoom Fridays 9:30a-12p Mtn GMT-6 bit.ly/virtualfriam > un/subscribe > https://linkprotect.cudasvc.com/url?a=http%3a%2f%2fredfish.com%2fmailman%2flistinfo%2ffriam_redfish.com&c=E,1,oE6ONbGNZTopfmKhqX_Zb5UOMgb9n69_1X6YikFJV5DsGn6e2X3OFjkKnWgQjf4dTvoDReRt8y4aK870nmnkx3zE02uGnLfqcQ6QwSmXjmNLKpQ0-p9rIgo,&typo=1 > FRIAM-COMIC > https://linkprotect.cudasvc.com/url?a=http%3a%2f%2ffriam-comic.blogspot.com%2f&c=E,1,VaG5q3IidNA_vxIkWSqQiftC8Tr540o_QuoNwaFxN_Pm-KQfVoToJg0wb1vxrIxIaQdLmj2cDjhEnCI_mpD3lpPQCFLrwxLBzVY4dTeEBpqZC-6dy6cap20NyOw,&typo=1 > archives: http://friam.471366.n2.nabble.com/
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