It's not the accumulation of damage and the fault/disease risk
associated with such damage that seems like pseudoscience. That's
actual science. But it starts to feel pseudo- when used to refine from
a big data population size to individual humans (or demographics). The
idea you can hop down to the lab, get the panel taken, and get a low
enough variance estimate of your biological age is pseudoscience.
Good clarification... I *was* missing your point... as I expected I was!
Take a look at Panel A of Figure 3 here:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940111/
Precision medicine is a grand challenge in most medical domains. We
haven't achieved it anywhere as far as I can tell. Eric's right,
though, that *where* a causal mechanism can be identified (e.g. in
developmental diseases), it can be targeted. But when you increase the
number of markers and nonlinear effects arise, you end up relying on
comparisons to an over-simplified aggregator (mean or median or
whatever). And any therapy becomes treatment to the lowest common
denominator.
My very limited experience with western medicine (professional and
amateur) seems highly biased toward this (LCD). Like smearing all the
colors together from your big box of crayons just gives you mud...
Maybe pseudoscience is too strong a word... since my focus is on the
word "premature" as opposed to statistical estimates of mortality,
maybe I can simply call it hyperbole? I guess it's akin to all the
hype around LLMs.
There is certainly no end of naive interpretation of statistics in our
popular descriptions of just about anything... unto superstition. I
know many people who very literally get very squirmy when they approach
the age that their same-sex parent died... especially if it was some
genetically influenced thing, but it could even have been a car-accident?!
I think watching the 'Publicans thrash on the House Floor over
McCarthy-or-not/bust today lowered my BP by at least 10 points...
nothing does my heart more good than watching the obstructors get in one
another's way for a change... especially watching Boebert's and
Greene's rants and Jordan's and Gaetz's and Biggs', and McCarthy's
smarmy attempts to normalize what is going on... while the usually
"litter-of-puppies" styled Dems all lined up with a smile behind Jeffries...
Soon enough it will get old though...
On 1/3/23 12:08, Steve Smith wrote:
What part of telomeric erosion/degradation/consumption and/or
accumulated genetic damage via toxins and ionizing radiation (over a
lifetime)seems like pseudoscience? I'm probably missing your point.
On 1/3/23 11:01 AM, glen wrote:
Biological age just seems like pseudoscience to me, the flip side of
Vampirism. I'd welcome an education, though.
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