Definitely one to watch. I had presumed this approach to circumventing existing patents had been discouraged by the broad implications of the "inherently similar to" clauses which aim to legally distinguish one drug or invention from another, yet if the change within a particular medicine is significant enough to pass for unique, how is it that the knock-off medicines have not stumbled upon such an approach? I understand the knock-offs come after the protected patent periods, and that they are licensed by government bodies. Perhaps it's simply that the profit margin is the sole incentive, and beyond that the knock-off company could care less. Whatever the reason, at least it's finally a news item that restores hope in the research efforts of some groups. It's a clear example of how corporatism shapes social issues, globally.
Perhaps it's time that such products be recognized nationally and internationally to be socially restorative and nation saving, and therefore need to be redefined as or for their humanitarian benefits, rather than remain mere profit tools of medicine. I can't put my finger on it eloquently enough, but it is current law that will determine the outcome of such a decision. Changing the law to ensure corporations serve people rather than people serving the corporation is key to major social change; changing corporate laws to become socially responsible is essential for sustainable growth. Natalia Kuzmyn *********************************************** M.Blackmore wrote: >In case anyone here has missed this. Wonder how it will work out in real >life praxis - will the US and bigpharmacorpRATS actually allow this to >happen??? > > > > > > Medical Breakthrough Could Change Global Politics > By Chris Floyd > t r u t h o u t | UK Correspondent > > Tuesday 16 January 2007 > > I. The Biochemistry of Hope > > More war in Iraq. A new front in Somalia. Ships, troops and planes > lurking on the borders of Iran. Every day seems to deepen the shadow > over the dark valley of our times. Driven by a reckless regime in > Washington and the increasingly strident reaction it provokes, and by >growing financial and social inequities stranding billions of people in >poverty and despair, the geopolitical scene appears locked in a cycle of > conflict and chaos that nothing can break. > > But a quiet announcement at London's Hammersmith Hospital at the > turning of the new year heralded a breakthrough that has the potential > to be one of the most transformative developments ever seen in global > affairs: a positive change on a par with - or even surpassing - the > world-altering malignancies of war, greed and strife. But this boon > could be strangled in its cradle by the vast corporate interests > threatened by its radical new approach to both health care and > business. > > The approach is called "ethical pharmaceuticals," and it was >unveiled on January 2 by Sunil Shaunak, professor of infectious diseases > at Imperial College, and Steve Brocchini of the London School of > Pharmacy, the Guardian reports. Their team of scientists in India and > the UK, financed by the prestigious Wellcome with technical assistance > from the UK government, have developed a method of making small but > significant changes to the molecular structure of existing drugs, >thereby transforming them into new products, circumventing the long-term >patents used by the corporate giants of Big Pharma to keep prices - and > profits - high. This will give the world's poorest and most vulnerable > people access to life-saving medicines - now priced out of reach - for > mere pennies. > > But the breakthrough is not merely biochemical. Shaunak's team is >proposing a new model for the pharmaceutical business. The patent of the > transformed drug they have developed is held by non-profit Imperial > University. And because their methods are hundreds of millions dollars > cheaper than the mammoth development costs of the big pharmaceutical > companies - whose spending on marketing and advertising often dwarfs > their funding of scientific research - Shaunak and his colleagues can > market their vital medicines for infectious diseases at near-giveaway > levels, yet still stay in business. How so? By foregoing the profit > motive as the ultimate value of their work. > > "People in academic medicine have a choice," Shaunak told an > Imperial College journal. "They can use their ideas and creativity to > make large sums of money for small numbers of people, or they can look > outwards to the global community and make affordable treatments for > common diseases." > > The first drug developed by the team is a new version of interferon, >the main treatment for Hepatitis C, a debilitating disease that afflicts > 200 million people worldwide. Yet only 30 million can afford the > medicine. That leaves the rest to face the chronic liver disease and > premature death that the illness inflicts. The cost of Hepatitis C > treatment in the UK is approximately $13,000 per patient per year, New >Scientist reports. Nor can a cheaper version of the existing interferon >be made, because Big Pharma players Hoffman-La Roche and Schering Plough >hold patents not only on the drug but also on the standard way of adding > the special molecules needed to enhance its performance. > > So Shaunak and Brocchini invented a new way attaching the molecules > - from the inside, not the outside - that went around the patent >restrictions and produced a medicine that "appears to be as effective as > the existing product," according to Nature, the leading scientific > journal. Their novel methods could also be adapted to extend the >effectiveness of "drugs for other conditions such as HIV," at a fraction > of current costs, Shaunak told New Scientist. Big Pharma says it costs >an average of $800 million to create a new drug; but without the need to > produce ever-expanding profits for shareholders or use glitzy ad >campaigns to push their pills - or lay out the vast political patronage > that Big Pharma dispenses each year to keep its favored politicians > sweet - Shaunak says his team can now develop essential medicines for > only a few million dollars each. > > In fact, while their Hepatitis C medicine undergoes > government-funded clinical trials in India, Shaunak and Brocchini have >been asked by Médecins Sans Frontières to work on treatments for another >ailment: Leishmaniasis, a parasitical disease also known as black fever. > It "occurs in the poorer parts of the world: India, around the > Mediterranean, South America, Sudan," Shaunak told Spero News. "Again, > there is a treatment that cures the disease but in places like Bihar, > India, the cost of the drug is 80 percent of a person's annual income. > What we are going to do is make a version of the drug which will be >stable in hot climates and which will cost about 10 percent of the price > of the existing medicine." > > The potential benefits and geopolitical implications of this > approach are almost limitless. Imagine a world where the most >downtrodden can be rescued from the ravages of chronic disease that now >beset them, generation after generation. A world where they don't droop >and languish, where their energies are not consumed and exhausted in the >struggle for survival. A world where their children are born to healthy > mothers, with all the proven advantages for future development, both > physically and mentally, that such a birth provides. Imagine a world > where the preventable deaths and epidemics that break down societal >bonds, devastate communities, cripple local economies, destroy families > and make any kind of political action almost impossible are a thing of > the past. Whole new polities, new movements, new philosophies, new > centers of power would be created as the majority of humanity - the >untold multitudes who simply "don't matter" now, who live and die on the >ragged margins, in the mega-slums and shattered villages, the industrial > wastelands and war-scarred regions - are finally liberated from the > tyranny of chronic disease. Imagine the kind of politics that could > emerge from millions of long-forgotten people suddenly given more >strength, more longevity, more time and energy to seek political change > and redress of grievances rather than merely fighting to stay alive. > > It would be the political, social and cultural equivalent of the >discovery of the "New World," which transformed global affairs forever. > Only this time, the "natives" would be healed and empowered by the >encounter, not decimated and marginalized by disease and dispossession. > > We're not speaking here of "miracle cures" for all ailments, but > simply of access to the kind of basic health care that is considered > normal in the developed world. Of course, millions in these more >privileged countries also suffer needless debilitation from the firewall > of profit and price that surrounds so many medical advances. And here >too, "ethical pharmaceuticals" could also have a large political effect. > Once the drugs pass medical trials in India and elsewhere, they can be > sold in many nations in the developed world. Britain's National Health > Service, for example, would be able to use the Shaunak-Brocchini > treatment for Hepatitis C, saving tens of millions of dollars for the > public health service every year: money that could then be used for >treating other diseases, for preventive care, for improving facilities - > a virtuous circle rippling outward through society. > > II. Pushbacks and Politics > > Of course, the American people would doubtless be "protected" from >such radical virtue by its benevolent government, which even now shields > them from the menace of "unsafe" low-cost prescription drugs from > Canada. (For as we all know, al Qaeda has thoroughly infiltrated > Canada's commie-style health care system and is hoping to flood the > Homeland with polonium-laced heart pills and exploding suppositories > from Montreal and Saskatoon.) A strong bipartisan consensus in >Washington has long fought off the importation of dubious nostrums from >devilish foreigners. And although this tender concern for the wellbeing > of the American people has never quite extended to actually providing > them with guaranteed health care, it has - no doubt coincidentally - >done wonders for the coffers of the major pharmaceutical companies, who >have reciprocated by showering their largesse on these dedicated public > officials. > > The power of this relationship has just been demonstrated once again > on Capitol Hill, as the Washington Post noted on Friday. The > newly-empowered Democratic majority in Congress has scaled back its > once-bold plans to overhaul George W. Bush's disastrous Medicare drug > program, which bollixed the medical care of millions of Americans but > has proven to be a bonanza for Big Pharma. (As well it should, seeing > how pharmaceutical lobbyists wrote most of the bill.) Now, instead of > their original plan to create a federal prescription-drug program that >would genuinely benefit the majority of the populace, the Democrats are >offering an anemic measure that would require the government to use its >buying power to negotiate lower drug prices for Medicare patients. Even > this would be an improvement over the current boondoggle, but it is of >course foredoomed to failure: Bush has already promised to veto it, and > the Democrats are unlikely to muster enough votes to override his > rejection. > > That's because, as the Post reports, "drug firms and their trade >groups have been transforming their Washington operations by hiring top > Democratic lobbyists to gain access to new committee chairmen, > bolstering Democratic political donations and spending millions on > public relations campaigns to overcome an image, indicated in recent >surveys, that the industry puts profits ahead of patients." (More money > that could have been spent on developing cheaper cures for, say, > Hepatitis C or Leishmaniasis.) > > In fact, Big Pharma has laid out more loot for American politicians > "than any other industry between 1998 and 2005 - more than $900 > million," the Post reports. For that amount of money, the > Shaunak-Brocchini method could have produced some 90 new low-cost > treatments for deadly infectious diseases around the world. > > With this kind of political muscle behind it, Big Pharma will be > well-placed to launch its inevitable push-back against ethical > pharmaceuticals. They are already limbering up the legal artillery for > possible patent infringement suits against the Shaunak team - although > the latter, through Imperial College, has also procured some big legal > guns to protect the process, including top lawyers who have worked for > Big Pharma itself, the Guardian reports. With press releases and > pro-industry articles from friendly journalists in conservative UK >papers, the corporations are also mounting a PR campaign against the new > drug development method, and defending their huge profit margins as > essential for continuing the industry's service to humanity. > > And it's true that the drugs developed by major pharmaceutical firms > have been of tremendous service to humanity over the years. Of course, > most of the time these benefits have gone to that portion of humanity > that can afford to pay for them, but not always. In the case of some > high-profile diseases, like AIDS, the industry has - often belatedly, > sometimes reluctantly and sometimes with genuine altruism - provided > some treatments at low cost, or even no cost. > > The irony is that Shaunak - who with his colleagues is now in the >cross-hairs of Big Pharma - cheerfully acknowledges the industry's good > works, and doesn't see his own researches as a threat. As he noted to > Spero News, his team is focused on providing medicines for people who > are getting no treatment at all. The drug companies are not making any > money from these sufferers; therefore they won't lose money if someone > else provides help for them. "These patients are simply getting no >treatment because the medicines are so expensive," he said. "As somebody >working within a university, I have a mission statement [to] try to make >drugs available for patients who currently have no treatment at all. So > in many ways our approach is complementary and not competitive to the > big pharmaceutical approaches." > > Complementary in many ways, yes, but not in all; for there's no > doubt that as ethical pharmaceuticals seep from the desolate areas of > the earth where Big Pharma can mine no medical gold into the developed >nations, it will erode the industry's towering profit margins. The drug >companies will have to learn to live within somewhat more modest means - >perhaps shaving a bit from the multimillion-dollar compensation packages >of its executives - or else shell out even more around the world for the >kind of political protection it now buys in Washington. Either way, even > here, in this very modest beginning, the new political and financial > power of the world's forgotten multitudes will begin to make itself > felt. > > Of course it may well be that the development of ethical > pharmaceuticals, like most human endeavors, will not achieve its full > potential. It may well be that powerful forces will combine to kill or > cripple it. But for now at least, it stands as a reminder that in the > course of human events, the ultimate ends are always unknown. Cycles, >systems, patterns of behavior and immense structures of power that seem > so fixed and immutable today will be swept away tomorrow, in ways that >we cannot begin to fathom. In dark days that seem locked in a glide-path > to disaster, these glimmers of possibility can perhaps offer some > measure of hope. > > >________________________________________________________________________ > Chris Floyd is an American journalist. His weekly political column, > "Global Eye," ran in the Moscow Times from 1996 to 2006. His work has >appeared in print and online in venues all over the world, including The >Nation, Counterpunch, Columbia Journalism Review, the Christian Science > Monitor, Il Manifesto, the Bergen Record and many others. His story on >Pentagon plans to foment terrorism won a Project Censored award in 2003. >He is the author of Empire Burlesque: High Crimes and Low Comedy in the > Bush Imperium, and is co-founder and editor of the "Empire Burlesque" > political blog. > > > > > > >_______________________________________________ >Futurework mailing list >[email protected] >http://fes.uwaterloo.ca/mailman/listinfo/futurework > > _______________________________________________ Futurework mailing list [email protected] http://fes.uwaterloo.ca/mailman/listinfo/futurework
