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Selma

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There's a Sucker Born in Every Medial Prefrontal Cortex

October 26, 2003
 By CLIVE THOMPSON 



 

When he isn't pondering the inner workings of the mind,
Read Montague, a 43-year-old neuroscientist at Baylor
College of Medicine, has been known to contemplate the
other mysteries of life: for instance, the Pepsi Challenge.
In the series of TV commercials from the 70's and 80's that
pitted Coke against Pepsi in a blind taste test, Pepsi was
usually the winner. So why, Montague asked himself not long
ago, did Coke appeal so strongly to so many people if it
didn't taste any better? 

Over several months this past summer, Montague set to work
looking for a scientifically convincing answer. He
assembled a group of test subjects and, while monitoring
their brain activity with an M.R.I. machine, recreated the
Pepsi Challenge. His results confirmed those of the TV
campaign: Pepsi tended to produce a stronger response than
Coke in the brain's ventral putamen, a region thought to
process feelings of reward. (Monkeys, for instance, exhibit
activity in the ventral putamen when they receive food for
completing a task.) Indeed, in people who preferred Pepsi,
the ventral putamen was five times as active when drinking
Pepsi than that of Coke fans when drinking Coke. 

In the real world, of course, taste is not everything. So
Montague tried to gauge the appeal of Coke's image, its
''brand influence,'' by repeating the experiment with a
small variation: this time, he announced which of the
sample tastes were Coke. The outcome was remarkable: almost
all the subjects said they preferred Coke. What's more, the
brain activity of the subjects was now different. There was
also activity in the medial prefrontal cortex, an area of
the brain that scientists say governs high-level cognitive
powers. Apparently, the subjects were meditating in a more
sophisticated way on the taste of Coke, allowing memories
and other impressions of the drink -- in a word, its brand
-- to shape their preference. 

Pepsi, crucially, couldn't achieve the same effect. When
Montague reversed the situation, announcing which tastes
were of Pepsi, far fewer of the subjects said they
preferred Pepsi. Montague was impressed: he had
demonstrated, with a fair degree of neuroscientific
precision, the special power of Coke's brand to override
our taste buds. 

Measuring brand influence might seem like an unusual
activity for a neuroscientist, but Montague is just one of
a growing breed of researchers who are applying the methods
of the neurology lab to the questions of the advertising
world. Some of these researchers, like Montague, are purely
academic in focus, studying the consumer mind out of
intellectual curiosity, with no corporate support.
Increasingly, though, there are others -- like several of
the researchers at the Mind of the Market Laboratory at
Harvard Business School -- who work as full-fledged
''neuromarketers,'' conducting brain research with the help
of corporate financing and sharing their results with their
sponsors. This summer, when it opened its doors for
business, the BrightHouse Institute for Thought Sciences in
Atlanta became the first neuromarketing firm to boast a
Fortune 500 consumer-products company as a client. (The
client's identity is currently a secret.) The institute
will scan the brains of a representative sample of its
client's prospective customers, assess their reactions to
the company's products and advertising and tweak the
corporate image accordingly. 

Not long ago, M.R.I. machines were used solely for medical
purposes, like diagnosing strokes or discovering tumors.
But neuroscience has reached a sort of cocky adolescence;
it has become routine to read about researchers tackling
every subject under the sun, placing test subjects in
M.R.I. machines and analyzing their brain activity as they
do everything from making moral choices to praying to
appreciating beauty. Paul C. Lauterbur, a chemist who
shared this year's Nobel Prize in medicine for his
contribution in the early 70's to the invention of the
M.R.I. machine, notes how novel the uses of his invention
have become. ''Things are getting a lot more subtle than
we'd ever thought,'' he says. It seems only natural that
the commercial world has finally caught on. ''You don't
have to be a genius to say, 'My God, if you combine making
the can red with making it less sweet, you can measure this
in a scanner and see the result,''' Montague says. ''If I
were Pepsi, I'd go in there and I'd start scanning
people.'' 


The neuroscience wing at Emory University Hospital in
Atlanta is the epicenter of the neuromarketing world. Like
most medical wards, it is filled with an air of quiet,
antiseptic tension. On a recent visit, in the hallway
outside an M.R.I. room, a patient milled around in a light
blue paper gown. A doctor on a bench flipped through a
clipboard and talked in soothing tones to a man in glasses,
a young woman anxiously clutching his arm. 

It was not a place where you would expect to encounter
slick marketing research. And when Justine Meaux, a
research scientist for the BrightHouse Institute, came out
to greet me, she did seem strangely out of place. Clicking
along in strappy sandals, with a tight sleeveless top and
purple toenail polish, she looked more like a chic TV
producer than a neuroscientist, which she is. Her
specialty, as she explained, is ''the neural dynamics of
the perception and production of rhythmic sensorimotor
patterns'' -- though these days she spends her professional
life thinking about shopping. ''I'm really getting into
reading all this business stuff now, learning about
campaigns, branding,'' she said, leading me down the
hallway to the M.R.I. chamber that the Institute uses.
Three years ago, after earning her Ph.D., she decided she
wanted to apply brain scanning to everyday problems and was
intrigued by marketing as a ''practical application of
psychology,'' as she put it. She told me that she admired
the ''Intel Inside'' advertising campaign, with its TV
spots showing dancing men in body suits. ''Intel actually
branded the inside of a computer,'' she marveled. ''They
took the most abstract thing you can imagine and figured
out a way to make people identify with it.'' 

When we reached the M.R.I. control room, Clint Kilts, the
scientific director of the BrightHouse Institute, was
fiddling away at a computer keyboard. A professor in the
department of psychiatry and behavioral sciences at Emory,
Kilts began working with Meaux in 2001. Meaux had learned
that Kilts and a group of marketers were founding the
BrightHouse Institute, and she joined their team, becoming
perhaps the world's first full-time neuromarketer. Kilts is
confident that there will soon be room for other full-time
careers in neuromarketing. ''You will actually see this
being part of the decision-making process, up and down the
company,'' he predicted. ''You are going to see more large
companies that will have neuroscience divisions.'' 

The BrightHouse Institute's techniques are based, in part,
on an experiment that Kilts conducted earlier this year. He
gathered a group of test subjects and asked them to look at
a series of commercial products, rating how strongly they
liked or disliked them. Then, while scanning their brains
in an M.R.I. machine, he showed them pictures of the
products again. When Kilts looked at the images of their
brains, he was struck by one particular result: whenever a
subject saw a product he had identified as one he truly
loved -- something that might prompt him to say, ''That's
just so me!'' -- his brain would show increased activity in
the medial prefrontal cortex. 

Kilts was excited, for he knew that this region of the
brain is commonly associated with our sense of self.
Patients with damage in this area of the brain, for
instance, often undergo drastic changes in personality; in
one famous case, a mild-mannered 19th-century railworker
named Phineas Gage abruptly became belligerent after an
accident that destroyed his medial prefrontal cortex. More
recently, M.R.I. studies have found increased activity in
this region when people are asked if adjectives like
''trustworthy'' or ''courageous'' apply to them. When the
medial prefrontal cortex fires, your brain seems to be
engaging, in some manner, with what sort of person you are.
If it fires when you see a particular product, Kilts
argues, it's most likely to be because the product clicks
with your self-image. 

This result provided the BrightHouse Institute with an
elegant tool for testing marketing campaigns and brands. An
immediate, intuitive bond between consumer and product is
one that every company dreams of making. ''If you like
Chevy trucks, it's because that has become the larger
gestalt of who you self-attribute as,'' Kilts said, using
psychology-speak. ''You're a Chevy guy.'' With the help of
neuromarketers, he claims, companies can now know with
certainty whether their products are making that special
connection. 

To demonstrate their technique, Kilts and Meaux offered to
stick my head in the M.R.I. machine. They laid me down
headfirst in the coffinlike cylinder and scurried out to
the observation room. ''Here's what I want you to do,''
Meaux said, her voice crackling over an intercom. ''I'm
going to show you a bunch of images of products and
activities -- and I want you to picture yourself using
them. Don't think about whether you like them or not. Just
put yourself in the scene.'' 

I peered up into a mirror positioned over my head, and she
began flashing pictures. There were images of a Hummer, a
mountain bike, a can of Pepsi. Then a Lincoln Navigator,
Martha Stewart, a game of basketball and dozens more
snapshots of everyday consumption. I imagined piloting the
Hummer off-road, playing a game of pickup basketball,
swigging the Pepsi. (I was less sure what to do with Martha
Stewart.) 

After about 15 minutes, Kilts pulled me out, and I joined
him at a bank of computers. ''Look here,'' he said,
pointing to a screen that showed an image of a brain in
cross sections. He pointed to a bright yellow spot on the
right side, in the somatosensory cortex, an area that shows
activity when you emulate sensory experience -- as when I
imagined what it would be like to drive a Hummer. If a
marketer finds that his product is producing a response in
this region of the brain, he can conclude that he has not
made the immediate, instinctive sell: even if a consumer
has a positive attitude toward the product, if he has to
mentally ''try it out,'' he isn't instantly identifying
with it. 

Kilts stabbed his finger at another glowing yellow dot near
the top of the brain. It was the magic spot -- the medial
prefrontal cortex. If that area is firing, a consumer isn't
deliberating, he said: he's itching to buy. ''At that
point, it's intuitive. You say: 'I'm going to do it. I want
it.' '' 

The consuming public has long had an uneasy feeling about
scientists who dabble in marketing. In 1957, Vance Packard
wrote ''The Hidden Persuaders,'' a book about marketing
that featured harsh criticism of ''psychology professors
turned merchandisers.'' Marketers, Packard worried, were
using the resources of the social sciences to understand
consumers' irrational and emotional urges -- the better to
trick them into increased product consumption. In
rabble-rousing prose, Packard warned about subliminal
advertising and cited a famous (though, it turned out,
bogus) study about a movie theater that inserted into a
film several split-second frames urging patrons to drink
Coke. 

In truth, marketers only wish they had that much control.
If anything, corporations tend to look slightly askance at
their admen, because there's not much convincing evidence
that advertising works as well as promised. John Wanamaker,
a department-store magnate in the late 19th century,
famously quipped that half the money he spent on
advertising was wasted, but that he didn't know which half.
In their quest for a more respectable methodology -- or
perhaps more important, the appearance of one -- admen have
plundered one scientific technique after another.
Demographic studies have profiled customers by analyzing
their age, race or neighborhood; telephone surveys have
queried semi-randomly selected strangers to see how the
public at large viewed a company's product. 

Advertising's main tool, of course, has been the focus
group, a classic technique of social science. Marketers in
the United States spent more than $1 billion last year on
focus groups, the results of which guided about $120
billion in advertising. But focus groups are plagued by a
basic flaw of human psychology: people often do not know
their own minds. Joey Reiman is the C.E.O. of BrightHouse,
an Atlanta marketing firm, and a founding partner in the
BrightHouse Institute; over years of producing marketing
concepts for companies like Coca-Cola and Red Lobster, he
has come to the conclusion that focus groups are ultimately
less about gathering hard data and more about pretending to
have concrete justifications for a hugely expensive ad
campaign. ''The sad fact is, people tell you what you want
to hear, not what they really think,'' he says. ''Sometimes
there's a focus-group bully, a loudmouth who's so insistent
about his opinion that it influences everyone else. This is
not a science; it's a circus.'' 

In contrast, M.R.I. scanning offers the promise of concrete
facts -- an unbiased glimpse at a consumer's mind in
action. To an M.R.I. machine, you cannot misrepresent your
responses. Your medial prefrontal cortex will start firing
when you see something you adore, even if you claim not to
like it. ''Let's say I show you Playboy,'' Kilts says,
''and you go, 'Oh, no, no, no!' Really? We could tell you
actually like it.'' 

Other neuromarketers have demonstrated that we react to
products in ways that we may not be entirely conscious of.
This year, for instance, scientists working with
DaimlerChrysler scanned the brains of a number of men as
they looked at pictures of cars and rated them for
attractiveness. The scientists found that the most popular
vehicles -- the Porsche- and Ferrari-style sports cars --
triggered activity in a section of the brain called the
fusiform face area, which governs facial recognition.
''They were reminded of faces when they looked at the
cars,'' says Henrik Walter, a psychiatrist at the
University of Ulm in Germany who ran the study. ''The
lights of the cars look a little like eyes.'' 

Neuromarketing may also be able to suss out the distinction
between advertisements that people merely like and those
that are actually effective -- a difference that can be
hard to detect from a focus group. A neuromarketing study
in Australia, for instance, demonstrated that supershort,
MTV-style jump cuts -- indeed, any scenes shorter than two
seconds -- aren't as likely to enter the long-term memory
of viewers, however bracing or aesthetically pleasing they
may be. 

Still, many scientists are skeptical of neuromarketing. The
brain, critics point out, is still mostly an enigma; just
because we can see neurons firing doesn't mean we always
know what the mind is doing. For all their admirable
successes, neuroscientists do not yet have an agreed-upon
map of the brain. ''I keep joking that I could do this
Gucci shoes study, where I'd show people shoes I think are
beautiful, and see whether women like them,'' says
Elizabeth Phelps, a professor of psychology at New York
University. ''And I'll see activity in the brain. I
definitely will. But it's not like I've found 'the shoe
center of the brain.''' James Twitchell, a professor of
advertising at the University of Florida, wonders whether
neuromarketing isn't just the next stage of scientific
pretense on the part of the advertising industry.
''Remember, you have to ask the client for millions,
millions of dollars,'' he says. ''So you have to say:
'Trust me. We have data. We've done these neurotests. Go
with us, we know what we're doing.''' Twitchell recently
attended an advertising conference where a marketer
discussed neuromarketing. The entire room sat in awe as the
speaker suggested that neuroscience will finally crack open
the mind of the shopper. ''A lot of it is just garbage,''
he says, ''but the garbage is so powerful.'' 

In response to his critics, Kilts plans to publish the
BrightHouse research in an accredited academic journal. He
insisted to me that his primary allegiance is to science;
BrightHouse's techniques are ''business done in the science
method,'' he said, ''not science done in the business
method.'' And as he sat at his computer, calling up a 3-D
picture of a brain, it was hard not to be struck, at the
very least, by the seriousness of his passion. There, on
the screen, was the medial prefrontal cortex, juggling our
conscious thinking. There was the amygdala, governing our
fears, buried deep in the brain. These are sights that he
said still inspire in him feelings of wonder. ''When you
sit down and you're watching -- for the first time in the
history of mankind -- how we process complex primary
emotions like anger, it's amazing,'' he said. ''You're
like, there, look at that: that's anger, that's pleasure.
When you see that roll off the workstation, you never look
back.'' You just keep going, it seems, until you hit
Madison Avenue. 




Clive Thompson writes frequently about science and
technology. His most recent article for the magazine was
about the future of kitchen tools. 

http://www.nytimes.com/2003/10/26/magazine/26BRAINS.html?ex=1068177670&ei=1&en=c8fe862e1d0b7cee


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