I had a similar issue a while ago. Greg mentioned the following setting in universe:

# Enable use of an in-memory registry with bi-directional relationships
# between repositories (i.e., in addition to lists of dependencies for a
# repository, keep an in-memory registry of dependent items for each repository.
#manage_dependency_relationships = True


Setting this to false made the delay go away. I haven't had issues so far after disabling.

See here for details: http://lists.bx.psu.edu/pipermail/galaxy-dev/2014-March/018821.html

Best,

Geert


On 08/05/2014 09:01 PM, Dannon Baker wrote:
There's definitely a request that will occasionally block at startup -- I've hit this before too, Martin. Looking into it now.


On Tue, Aug 5, 2014 at 2:59 PM, Martin Čech <mar...@bx.psu.edu <mailto:mar...@bx.psu.edu>> wrote:

    I just freshly cloned galaxy-central, switched to next-stable and
    did initial startup - no problems detected and Galaxy booted in
    under 2m.


    On Tue, Aug 5, 2014 at 2:54 PM, Langhorst, Brad <langho...@neb.com
    <mailto:langho...@neb.com>> wrote:

        I’ve noticed that startup is very slow.

        It’s about 15 minutes for me to stop and restart my 4 daemons.
        It was much faster with galaxy on local storage.

        brad
        --
        Bradley W. Langhorst, Ph.D.
        Applications and Product Development Scientist

        On Aug 5, 2014, at 2:41 PM, Björn Grüning
        <bjoern.gruen...@gmail.com <mailto:bjoern.gruen...@gmail.com>>
        wrote:

        Hi all,

        does anyone encountered a long start-up delay with the recent
        next-stable and starting a instance from scratch?

        For me its hanging at:

        tool_shed.galaxy_install.migrate.check DEBUG 2014-08-05
        18:39:45,207 psycopg2 egg successfully loaded for postgres
        dialect

        for 3-5 minutes.

        Cheers,
        Bjoern
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    ___________________________________________________________
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___________________________________________________________
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--

Geert Vandeweyer, Ph.D.
Department of Medical Genetics
University of Antwerp
Prins Boudewijnlaan 43
2650 Edegem
Belgium
Tel: +32 (0)3 275 97 56
E-mail: geert.vandewe...@ua.ac.be
http://ua.ac.be/cognitivegenetics
http://www.linkedin.com/in/geertvandeweyer

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