Hi Brad,

this is known somewhat rare startup error. Please restart your Galaxy and
it should go away.

Dannon is tracking it down and this recent change might solve it:
https://github.com/galaxyproject/galaxy/pull/128

Martin

On Sun, Apr 19, 2015 at 2:53 PM Langhorst, Brad <langho...@neb.com> wrote:

>  InvalidRequestError: One or more mappers failed to initialize - can't
> proceed with initialization of other mappers.  Original exception was:
> Class 'kombu.transport.sqlalchemy.Message' is not mapped
> galaxy.jobs.handler ERROR 2015-04-19 14:46:00,794 Exception in monitor_step
> Traceback (most recent call last):
>   File "/mnt/galaxy/data/galaxy/galaxy-dist/lib/galaxy/jobs/handler.py",
> line 177, in __monitor
>     self.__monitor_step()
>   File "/mnt/galaxy/data/galaxy/galaxy-dist/lib/galaxy/jobs/handler.py",
> line 229, in __monitor_step
>     jobs_to_check =
> self.sa_session.query(model.Job).enable_eagerloads(False) \
>   File
> "/mnt/galaxy/data/galaxy/galaxy-dist/eggs/SQLAlchemy-0.9.8-py2.7-linux-x86_64-ucs2.egg/sqlalchemy/orm/scoping.py",
> line 150, in do
>     return getattr(self.registry(), name)(*args, **kwargs)
>   File
> "/mnt/galaxy/data/galaxy/galaxy-dist/eggs/SQLAlchemy-0.9.8-py2.7-linux-x86_64-ucs2.egg/sqlalchemy/orm/session.py",
> line 1165, in query
>     return self._query_cls(entities, self, **kwargs)
>   File
> "/mnt/galaxy/data/galaxy/galaxy-dist/eggs/SQLAlchemy-0.9.8-py2.7-linux-x86_64-ucs2.egg/sqlalchemy/orm/query.py",
> line 108, in __init__
>     self._set_entities(entities)
>   File
> "/mnt/galaxy/data/galaxy/galaxy-dist/eggs/SQLAlchemy-0.9.8-py2.7-linux-x86_64-ucs2.egg/sqlalchemy/orm/query.py",
> line 118, in _set_entities
>     self._set_entity_selectables(self._entities)
>   File
> "/mnt/galaxy/data/galaxy/galaxy-dist/eggs/SQLAlchemy-0.9.8-py2.7-linux-x86_64-ucs2.egg/sqlalchemy/orm/query.py",
> line 151, in _set_entity_selectables
>     ent.setup_entity(*d[entity])
>   File
> "/mnt/galaxy/data/galaxy/galaxy-dist/eggs/SQLAlchemy-0.9.8-py2.7-linux-x86_64-ucs2.egg/sqlalchemy/orm/query.py",
> line 3036, in setup_entity
>     self._with_polymorphic = ext_info.with_polymorphic_mappers
>   File
> "/mnt/galaxy/data/galaxy/galaxy-dist/eggs/SQLAlchemy-0.9.8-py2.7-linux-x86_64-ucs2.egg/sqlalchemy/util/langhelpers.py",
> line 725, in __get__
>     obj.__dict__[self.__name__] = result = self.fget(obj)
>   File
> "/mnt/galaxy/data/galaxy/galaxy-dist/eggs/SQLAlchemy-0.9.8-py2.7-linux-x86_64-ucs2.egg/sqlalchemy/orm/mapper.py",
> line 1877, in _with_polymorphic_mappers
>     configure_mappers()
>   File
> "/mnt/galaxy/data/galaxy/galaxy-dist/eggs/SQLAlchemy-0.9.8-py2.7-linux-x86_64-ucs2.egg/sqlalchemy/orm/mapper.py",
> line 2586, in configure_mappers
>     raise e
>
>
>  Once this error occurs, no more jobs execute on the cluster.
>
>  Restarting the handler seems to get things moving again, but I’d like to
> find the source of the failure.
>
>  Any ideas?
>
>
>  Brad
>   --
> Brad Langhorst, Ph.D.
> Applications and Product Development Scientist
>
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