Hi,
 
It's the first time for me to use cufflinks in galaxy, two choices confused me 
as follows:
Perform Bias Correction: 
 No Yes
Bias detection and correction can significantly improve accuracy of transcript 
abundance estimates. 

Set Parameters for Paired-end Reads? (not recommended): 
 No Yes
what is the Bias correction and how does it work? And for "set parameters for 
paired-end reads? (not recommended)" ,what would be important difference 
between recommended and not recommended? 
Thanks a lot!
dongdong
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