Hi Enis, Jeremy,

Thanks, that's really helpful! Jeremy do you remember what kind of
instance you used per node, e.g. Amazon's 'large' (2 core / 4ECU /
7.5GB) or 'xlarge' (4 core / 8ECU / 15GB)? This would be a good sanity
check for me.

Enis when you say a lot of memory, would you consider the 15GB nodes
'a lot'? I would generally consider that a lot in the context of a web
server but not so much in NGS, so it's all relative! Amazon does have
double-memory instances available.

Also, when you say a lot of memory especially for the master node -
does this imply that I can choose a different specification for the
master node than the compute nodes? I thought they had to be all
identical, but just checking.

Thanks,
Clare

On Fri, Nov 18, 2011 at 12:56 AM, Jeremy Goecks <jeremy.goe...@emory.edu> wrote:
>
>> Jeremy (from the team) ran a similar workshop several months ago and used 
>> some resource intensive tools (e.g., Tophat). We were concerned about the 
>> same scalability issues so we just started 4 separate clusters and divided 
>> the users across those. The approach worked well and it turned out we did 
>> not see any scalability issues. I think we went way overboard with 4 
>> clusters but the approach did demonstrate an additional 'coolness' of the 
>> project allowing one to spin up 4 complete, identical clusters in a matter 
>> of minutes...
>> So, I feel you could replicate a similar approach but could probably go with 
>> 2 clusters only? Jeremy can hopefully provide some first hand comments as 
>> well.
>
> Yes, this approach worked well when I did it. I created all the data and 
> workflows needed for the workshop on one Galaxy instance, shared/cloned that 
> instance and set up 3 additional instances, and divided users evenly amongst 
> the instances. 2-3 clusters will probably meet your needs with 50 
> participants.
>
> Scalability issues are more likely to arise on the back end than the front 
> end, so you'll want to ensure that you have enough compute nodes. BWA uses 
> four nodes by default--Enis, does the cloud config change this parameter?--so 
> you'll want 4x50 or 200 total nodes if you want everyone to be able to run a 
> BWA job simultaneously.
>
> Good luck,
> J.
>
>
>
>



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