I have python 2.7 and it seems to be the problem with it. Just formated
the partition I had linux and fresh install everything and still have same
problem.  I did what is recommended here too.
Check your Python version

Galaxy's core functionality is compatible with *Python* versions *2.5*, *2.6
*, and *2.7*. (Version 2.4 support was last included in the November 18,
Before reporting bugs, please ensure that python --version reports one of
these three versions. If this is not the case, a simple solution is to
manipulate your shell's $PATH variable to place the correct version first.
This can be done for only Python by creating a new directory at the front
of $PATH and creating a symbolic link to python in that directory:

Toggle line numbers <http://wiki.g2.bx.psu.edu/Admin/Get%20Galaxy#>

% mkdir ~/galaxy-python   2
% ln -s /path/to/python2.5 ~/galaxy-python/python   3
% export PATH=~/galaxy-python:$PATH

On Sat, Feb 25, 2012 at 5:50 PM, Luciano Cosme <cosme.sim...@gmail.com>wrote:

> *Hi Everyone,
>    I have been running a Local Galaxy instance for a long time, but now I
> am having some problems with uploading data. I am getting the following
> error:*
> Can't create peek [Errno 2] No such file or directory: 
> '/home/koala2/galaxy-dist/database/files/000/dataset_13.dat'
> *
> and from the Terminal:*
> - - [25/Feb/2012:17:45:00 -0500] "POST 
> /library_common/library_item_updates HTTP/1.1" 200 - 
> "
> sort=name&operation=browse&f-description=All&f-name=All&f-deleted=False&cntrller=library_admin&async=false&show_item_checkboxes=false&webapp=
> galaxy&id=f2db41e1fa331b3e&page=1" "Mozilla/5.0 (X11; Ubuntu; Linux x86_64; 
> rv:10.0.2) Gecko/20100101 Firefox/10.0.2"
> *   I reinstalled Unbutu and still having the same issue. I also removed 
> Postgresql 9.1 and reinstalled it. I that it might be an issue with 
> postgresql and not Galaxy, but I am not an expert.
>    Any suggestions will be appreciated.
> Thank you.
> Luciano
> *
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