> ---------- Forwarded message ---------
>
> Date: Fri, Mar 20, 2020 at 7:19 PM
> Subject: VITAMIN C MAY AFFECT LUNG INFECTIONS.
> Persedian Vitamin C di Apotek2 telah kosong, sudah diborong habis oleh
> semua orang2.
> Apalagi kini tersebar berita2 bahwa Vit C Infusions menolong dalam hal
> COVID-19.
> Dianjurkan 4- 6 gram  oral/TABLET  vitamin C  sangat menolong menurut
> berita2 itu.
>
> Dibawah sedikit cuplikan dari Google ---Article yang menjelaskan,
> begaimana Vit C bekerja
> dalam tubuh......:
> Vitamin C may affect lung infections
>
> Additional article information
> <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2099400/#__ffn_sectitle>
>
> Vitamin C was identified in the early 1900s in the search for a deficient
> substance responsible for scurvy, which was a serious disease of sailors in
> the Age of Sail. In the early literature, *scurvy was directly linked to
> pneumonia*. The American paediatrician Alfred Hess carried out extensive
> studies on scurvy and summarized autopsy findings as follows: ‘*pneumonia,
> lobular or lobar, is one of the most frequent complications [of scurvy] and
> causes of death*’ and ‘*secondary pneumonias, usually broncho-pneumonic
> in type, are of common occurrence, and in many [scurvy] epidemics
> constitute the prevailing cause of death*’.Starting in the 1930s, some
> German and US physicians proposed that vitamin C would be beneficial in the
> treatment of pneumonia. dramatically in developed countries during the past
> century, lung infections are still a leading cause of mortality and
> morbidity globally. Therefore, the question of whether vitamin C might
> affect pneumonia is an issue worthy of systematic consideration.
>
> The best known physiological* function of vitamin C is its participation
> in collagen hydroxylation*, and the symptoms of scurvy are largely
> explained by changes in collagen metabolism. The biochemistry of vitamin C
> is, however, much more complex. For example, it also participates in the
> enzymatic synthesis of dopamine, carnitine and a number of neuroendocrine
> peptides
>
> In the immune system, the major role of vitamin C seems to be as a
> physiological antioxidant, protecting host cells against oxidative stress
> caused by infections. Its concentration in phagocytes and lymphocytes is
> very high compared with the level in plasma, indicating that *vitamin C
> may have functional roles in these immune system cells.* In various
> experimental settings, vitamin C increased the functioning of phagocytes,
> the proliferation of T-lymphocytes and the production of interferon, and*
> decreased the replication of viruses.*
>
> Pneumonia, lead to reduced vitamin C levels in plasma, leukocytes and
> urine. Because of these changes in metabolism, *vitamin C might have a
> therapeutic effect on pneumonia patients. *Thus there is a biological
> rationale to examine the effect of vitamin C on infections in humans.
> A systematic review, published in the Cochrane Library, in which the role
> of vitamin C supplementation on preventing and treating pneumonia. three
> controlled trials reporting on the preventive effect and two on the
> therapeutic effect of vitamin C against pneumonia. Each of the trials found
> a statistically significant benefit of vitamin C supplementation on at
> least one clinically relevant outcome. In the therapeutic trials, vitamin C
> was tested over and above the normal medication, which included
> antibiotics. Two of the five trials were randomized, placebo-controlled
> double-blind trials. The other three trials were technically deficient to
> varying degrees, but their short-comings do not cause biases that would
> give evident explanations to the reported differences in favour of the
> vitamin C groups.
>
>
>  According to animal studies, vitamin C increases resistance to various
> viral and bacterial infections. Moreover, many infections,
> including...............
>
>
>
>

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