Hello Irina,
Thank you for reporting this problem. We were aware of a similar problem, but 
not the entire scope. We have plans to update the UCSC Gene's track and make as 
many corrections as possible soon.
Thanks,
Jennifer


------------------------------------------------ 
Jennifer Jackson 
UCSC Genome Bioinformatics Group 

----- "Irina Khrebtukova" <[email protected]> wrote:

> From: "Irina Khrebtukova" <[email protected]>
> To: [email protected]
> Sent: Tuesday, September 1, 2009 4:58:38 PM GMT -08:00 US/Canada Pacific
> Subject: [Genome] discrepancy between knownGenePep and Table-cds
>
> Hi,
> 
> I noticed some discrepancies between Table-tool generated coding
> sequences for known genes and posted on May 10 knownGenePep
> sequences.
> 
> For example, for the human gene SIPA1 there are 5 knowngenes in the
> hg18:
> SIPA1 (uc009yqq.1) at chr11:65164878-65174965 
> SIPA1 (uc009yqp.1) at chr11:65164168-65174965 
> SIPA1 (uc009yqo.1) at chr11:65162171-65174965 
> SIPA1 (uc001ofd.1) at chr11:65164168-65174965 
> SIPA1 (uc001ofb.1) at chr11:65162171-65174965 
> 
> #name chrom   strand  cdsStart        cdsEnd  proteinID
> uc009yqo.1    chr11   +       65164968        65169167
> NP_006738
> uc001ofb.1    chr11   +       65164968        65174762        Q96FS4
> uc009yqp.1    chr11   +       65164968        65169167
> NP_694985
> uc001ofd.1    chr11   +       65164968        65174762        Q96FS4
> uc009yqq.1    chr11   +       65164968        65174762        Q96FS4
> 
> getting cds sequences using Table-tool returns sequences of following
> lengths:
> 
> uc009yqo.1    1149 
> uc001ofb.1    3129
> uc009yqp.1    1149
> uc001ofd.1    3129
> uc009yqq.1    3129
> 
> which corresponds to shown in browser: two short and 3 longer
> proteins,
> 382 and 1042 aa. 
> 
> However in the knownGenePep.txt all 5 proteins are reported as longer
> version:
> 
> uc009yqo.1    1042
> uc001ofb.1    1042
> uc009yqp.1    1042
> uc001ofd.1    1042
> uc009yqq.1    1042
> 
> could you please clarify it?
> Thanks a lot!
> Irina Khrebtukova
> 
> _______________________________________________
> Genome maillist  -  [email protected]
> https://lists.soe.ucsc.edu/mailman/listinfo/genome
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