Hello Harry,

Making a liftOver seems like a reasonable request.  I am passing this on to our 
developers, and I hope to get back to you soon as to the status of this data.

Kayla Smith
UCSC Genome Bioinformatics Group

----- "Harry Noyes" <[email protected]> wrote:

> Dear UCSC
> As you probably know, the bovine community has got it self in to the 
> 
> unusual position of having two concurrent assemblies; Bta4 from the  
> Bovine Genome Consortium, that is the assembly used by UCSC, and MD3 
> 
> put together by Steve Salzberg's group at University of Maryland.  
> Whilst MD3 is probably a better assembly, Bta4 is certainly better  
> annotated and supported.
> 
> We are currently resequencing three bovine genome and I am aware of  
> other groups sequencing at least 11 more and we are all using MD3.0  
> for mapping our short reads to the bovine genome. It would be very  
> useful for us and presumably for the other groups if we could have a 
> 
> liftover resource to map between the assemblies. I assume that there 
> 
> is already an over.chain for Bta4. Would it be possible to create an 
> 
> over.chain for MD3? If you could provide the over.chains we could run 
> 
> liftover. We could then host the mapping on our own servers and I   
> have had informal agreement to install other services on the Bovine  
> Genome Database server and I have approached them about running a  
> liftover service.
> 
> Best of all would be if you could host the mapping at UCSC.
> 
> The MD3 assembly is available from
> ftp://ftp.cbcb.umd.edu/pub/data/Bos_taurus/
> 
> I could request letters of support from the other groups sequencing  
> bovine genomes if that would help in your decision making.
> 
> Best wishes
> 
> Harry
> 
> Harry Noyes
> Room 231 BioSciences Building
> University of Liverpool
> Crown Street
> Liverpool
> L69 7ZB
> 0151 795 4512
> www.genomics.liv.ac.uk/tryps
> [email protected]
> 
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