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Subject:        Re: algorithm in liftOver
Sent By
"Peng Yu" <[email protected]>         On:     January 5, 2010 12:55 PM
To:     [email protected]

On Tue, Dec 22, 2009 at 3:47 PM, Peng Yu <[email protected]> wrote:
> I don't find a paper that describes how liftOver works. Could somebody
> let me know the algorithm used in liftOver?
>
> Are the chain files be generated by aligning two version of gnomic
> sequence (say mm6, mm8)?
>
> Why there are no direct map between, say, mm6 and mm8?
>
> liftOver accept BED files? But the strand field is optional in BED
> files. Does liftOver guarantee that a gnomic location has to be map to
> the same strand ('+' or '-'), if the strand field in BED is not
> specified?
>



------------------------------------------------ 
Jennifer Jackson 
UCSC Genome Bioinformatics Group 
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