Nib files are supplanted by .2bit.
The main reasons are: 2bit are twice as efficient as nibs
in compression, and they incorporate maps for masking and N's
that are space-efficient.

A .2bit file also has an indexed-directory in it which
means that you can load it up with hundreds of thousands
of sequences and it will not complain.   A .nib file
has no directory and can only hold a single sequence.

This makes .nib a poor choice for assemblies with
scaffolds, and since the .2bit can do everything
that a .nib can do, it makes them obsolete.

There are utils like faToTwoBit that will
take care of the job.  There ar

twoBitMask
bptForTwoBit
faToTwoBit
twoBitInfo
twoBitToFa

And many other libraries in our system
know how to read .2bit files, including
BLAT of course.

twoBitInfo is handy as you can extract
any sequence or any region of a sequence
with it, or even just a list of all
the sequence-names.

-Galt

Finney, Richard (NIH/NCI) [E] wrote:
> There is a directory for hg18 nib files :            
> ftp://hgdownload.cse.ucsc.edu/gbdb/hg18/nib/ 
> But there is no similar directory in ftp://hgdownload.cse.ucsc.edu/gbdb/hg19/ 
> (causing great sadness).
> 
> What's the thinking here?  Are nib files evil? Obsolete? Coming soon?
> What think you?
> 
> 
> _______________________________________________
> Genome maillist  -  [email protected]
> https://lists.soe.ucsc.edu/mailman/listinfo/genome
_______________________________________________
Genome maillist  -  [email protected]
https://lists.soe.ucsc.edu/mailman/listinfo/genome

Reply via email to