Hello Jorje,

What you are seeing are the results from two distinct data tracks along 
with data from a table (kgXref) that includes the maximum linked 
reference IDs from all public sources. There could be errors. The table 
is intended to be used as a resource, not as a final answer.

The actual tracks (UCSC Genes and RefSeq Genes, among others) are the 
mappings for the data that are based on target sequence homology to the 
reference genome. And although those two tracks may not always agree, as 
they are generated by different processes, they are a better source (as 
you state) for the correct genome position.

If you want to use linked data, you may find the table kgAlias easier to 
use. It contains fewer types of linked information and so is less 
cluttered than the hgXref table.

Jennifer

---------------------------------
Jennifer Jackson
UCSC Genome Bioinformatics Group
http://genome.ucsc.edu/

On 2/17/10 2:07 AM, Jose Jorge Galan Retamal wrote:
> Dear all,
>
> I am trying to retrieve human mrna genomic intervals from the UCSC table
> browser (whole genome).
> I have noticed that the same mrna can be located on different genomic
> regions depending on the search you perform on the table browser.
> Two examples:
>
> *The AK310762 mrna*
>
> *Search 1:*
> clade: Mammal
> genome: Human
> assembly: GRCh37
> group: All Tables
> database: hg19
> table: kgXref
> region: position AK310762
> *results in: *
>
>
>   SIZE IDENTITY CHROMOSOME STRAND  START     END       cDNA   START  END  
> TOTAL
> ------------------------------------------------------------------------------
>   1352  100.0%         19     +  47105328  47113252  AK310762    23
> 1374  
> 1375<http://genome.ucsc.edu/cgi-bin/hgTables?position=chr19:47105328-47113252&all_mrna=pack&hgsid=152164491>
>
>
> *Search 2:*
> clade: Mammal
> genome: Human
> assembly: GRCh37
> group: All Tables
> database: hg19
> table: kgXref
> region: genome
> output format: select fields from primary and related tables
> selected fields:
>       hg19.kgXref.mRNA
>       hg19.refGene.chrom
>       hg19.refGene.strand
>       hg19.refGene.txStart
>       hg19.refGene.txEnd
> *the AK310762 mrna **appears in the output as:*
>
> hg19.kgXref.mRNA hg19.refGene.chrom hg19.refGene.strand
> hg19.refGene.txStart hg19.refGene.txEnd
> AK310762      chr14   +       90863326        90874617
>
>
>
>
> *The CR607619 mrna*
>
> *Search 1:*
> clade: Mammal
> genome: Human
> assembly: GRCh37
> group: All Tables
> database: hg19
> table: kgXref
> region: position CR607619
> *results in: *
>
>   SIZE IDENTITY CHROMOSOME STRAND  START     END       cDNA   START  END  
> TOTAL
> ------------------------------------------------------------------------------
>   1342  100.0%          7     -   5566815   5568363  CR607619     1
> 1342  
> 1343<http://genome.ucsc.edu/cgi-bin/hgTables?position=chr7:5566815-5568363&all_mrna=pack&hgsid=152164491>
>
> *Search 2:*
> clade: Mammal
> genome: Human
> assembly: GRCh37
> group: All Tables
> database: hg19
> table: kgXref
> region: genome
> output format: select fields from primary and related tables
> selected fields:
>       hg19.kgXref.mRNA
>       hg19.refGene.chrom
>       hg19.refGene.strand
>       hg19.refGene.txStart
>       hg19.refGene.txEnd
> *the CR607619* *mrna **appears in the output as:*
>
> hg19.kgXref.mRNA hg19.refGene.chrom hg19.refGene.strand
> hg19.refGene.txStart hg19.refGene.txEnd
> CR607619      chr17   -       79476998        79479827
>
>
> I have checked the actual locations for both AK310762 and CR607619
> mRNAs in the UCSC Genome browser.
> It seems that the actual positions for both mRNAs are those obtained
> in Searches 1.
> Therefore, it seems that there is a problem in linking the tables
> kgXref and refGene.
>
> I would be very grateful if someone could check this question and
> propose any solution for it.
>
> Best wishes,
>
> Jorge
> _______________________________________________
> Genome maillist  -  [email protected]
> https://lists.soe.ucsc.edu/mailman/listinfo/genome
_______________________________________________
Genome maillist  -  [email protected]
https://lists.soe.ucsc.edu/mailman/listinfo/genome

Reply via email to