Hello Will,

I was able to find an answer that addressed your question exactly. It 
includes direct comments from the algorithm's author, Adam Siepel:
https://lists.soe.ucsc.edu/pipermail/genome/2009-July/019616.html

If you need any more help, please let us know,
Thanks,
Jennifer

---------------------------------
Jennifer Jackson
UCSC Genome Informatics Group
http://genome.ucsc.edu/

On 3/29/10 12:30 PM, Will Liao wrote:
> This question most certainly has been asked an answered but here it goes
> anyways....
>
> I have short regions (<200bp) that I want to calculat phastCons scores for
> so I can compare the level of conservation.  I am thinking about just taking
> the mean for each but I suppose there has to be a better way.  Do you have
> any idea how I can do this?
>
>
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