Hello YU,

Use the liftOver utility to transform the data. This is in the kent 
source code, but also available pre-compiled for several platforms.

You may also want to review the web version of the tool to note the 
parameters we use for same-species lifts (most are default).

 From the downloads page, scroll down to "Source Downloads -> LiftOver 
tool" and follow the links.
http://hgdownload.cse.ucsc.edu/downloads.html

The usage for the program (type program at prompt without any arguments) 
explains the inputs. One of these is the appropriate over.chain file. 
For your case, hg18->hg19, the file is called hg18ToHg19.over.chain.gz 
and is located here for ftp: 
http://hgdownload.cse.ucsc.edu/goldenPath/hg18/liftOver/

If you need any help once you get started, please feel free to write 
back to the mailing list for more help. The mailing list archives also 
contain many questions w/ answers for liftOver-related topics. Search 
from this page:

    http://genome.ucsc.edu/contacts.html  ->
      "Search the Genome mailing list archives:"

Jennifer

---------------------------------
Jennifer Jackson
UCSC Genome Informatics Group
http://genome.ucsc.edu/

On 5/26/10 2:55 PM, Yuan Jian wrote:
> hi ucsc genome,
>
> I have BED file generated from hg18, how can I change it to hg19-based?
>
> thanks
> YU
>
>
>
>
>
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