Quick update:

If you are interested in exploring what SAMtools has to offer, here is 
link to their web site: samtools.sourceforge.net

On 6/2/10 2:39 PM, Jennifer Jackson wrote:
> Hi Shashi,
>
> SAMtools is a distinct software project, presented as a bundle of tools
> used to analyze Next-gen sequences and generate/analyze SAM/BAM format
> data. It sounds like you did not use this and were successful with
> Galaxy instead, but are having trouble getting the data back into the
> UCSC Browser.
>
> You will need to output the data in a format that meets one of the
> Custom track data file format requirements. This means that it will need
> at a minimum a track line and optionally a browser line. Load the data
> using the Custom track submission form, the same one that you used to
> load the original BAM data. Links on the submission form go to help
> documents that describe formatting rules. If your data is large,
> consider using a bigWig or bigBed data format.
>
> Custom track help, covers all types:
> http://genome.ucsc.edu/goldenPath/help/hgTracksHelp.html#CustomTracks
>
> Double check the formatting and submission method and see if some of
> this helps resolve the issue,
>
> Jennifer
>
> On 6/2/10 12:17 PM, Shashikant Pujar wrote:
>> Hello Jennifer
>> Thanks for your reply.  I am not familiar with SAMTools in UCSC Browser, so 
>> it is difficult for me to do the command line thing.
>> I tried to load the "Filter pileup" on to the UCSC Genome Browser within 
>> Galaxy, but it is not loading.  I also tried the tabular version of the 
>> "Filter pileup", with the same outcome.  Further, I tried to save the Filter 
>> pileup as a file and load it on the browser (outside Galaxy) but no luck.  
>> Any suggestions?
>> Shashi
>>
>> ________________________________________
>> From: Jennifer Jackson [[email protected]]
>> Sent: Wednesday, June 02, 2010 2:46 PM
>> To: Shashikant Pujar
>> Cc: [email protected]
>> Subject: Re: [Genome] Custom Track Question
>>
>> Hello Shashi,
>>
>> You have some choices:
>>
>> Using SAM Tools on the command line, samtools pileup -c will call
>> variants from the SAM/BAM alignments with BED output. This could be
>> loaded at a custom track. This may be the quickest method if your
>> dataset is very large.
>>
>> Or, you can use Galaxy and load the results as a custom track. Send your
>> existing BAM custom track data from the Table browser (if not too large)
>> or upload files directly, then after the analysis, view results in the
>> UCSC browser. At Galaxy, see "NGS: SAM Tools ->   Generate pileup&   Filter
>> pileup".
>>
>> Links from UCSC:
>>      http://genome.ucsc.edu/ ->   Galaxy (left blue bar)
>>      from Table browser: Check "Galaxy" box in output section
>> Or directly: http://galaxy.psu.edu/
>>
>> Hopefully this helps,
>> Jennifer
>>
>> ---------------------------------
>> Jennifer Jackson
>> UCSC Genome Informatics Group
>> http://genome.ucsc.edu/
>>
>> On 6/2/10 7:03 AM, Shashikant Pujar wrote:
>>> Hi
>>>
>>> I have loaded a custom track (Illumina NGS reads in BAM format of a 2Mb 
>>> region) on the UCSC Dog Genome Browser.  Is there a way I can extract all 
>>> SNPs and Indels between the custom track and canFam2?
>>>
>>> Thanks
>>>
>>> Shashi Pujar
>>> _______________________________________________
>>> Genome maillist  -  [email protected]
>>> https://lists.soe.ucsc.edu/mailman/listinfo/genome
> _______________________________________________
> Genome maillist  -  [email protected]
> https://lists.soe.ucsc.edu/mailman/listinfo/genome
_______________________________________________
Genome maillist  -  [email protected]
https://lists.soe.ucsc.edu/mailman/listinfo/genome

Reply via email to