Hi, I have gotten a explanation about this phenomenon from Adam Siepel . Thanks!
Elizabeth On Mon, Jun 14, 2010 at 5:52 PM, Huei-Hun Elizabeth Tseng < [email protected]> wrote: > Hi, I'm looking at the placental mammals phyloP scores (using the raw data > downloaded from FTP) and don't understand why sometimes the phyloP score is > higher when more species are missing. > > Example: > > chrX:24,916,507-24,916,644 > This region is perfectly conserved in all placental mammals, except alpaca > is completely missing. Perfectly conserved A/T scores 2.03, perfectly > conserved C/G scores 2.57 in Placental Mammal PhyloP Conservation. > > chr1:10,795,193-10,795,335 > This region is perfectly conserved in all placental mammals, except > alpaca, squirrel, and hyrax are completely missing. Perfectly conserved A/T > scores 2.19, perfectly conserved C/G scores 2.70 in Placental Mammal PhyloP > Conservation. > > Why is the first region's perfectly conserved phyloP scores lower than the > second, which has straightforwardly more missing placental mammals? > > Thanks, > Huei-Hun Elizabeth Tseng > _______________________________________________ Genome maillist - [email protected] https://lists.soe.ucsc.edu/mailman/listinfo/genome
