Good Morning Alex:

The values you get from the FTP download files are the original "correct"
values.

The values obtained from the table-browser are, as indicated, compressed
values that have a loss in resolution from the original "correct" values.
They are perfectly good for the purpose of making the graph on the 
genome-browser.

See also: http://genomewiki.ucsc.edu/index.php/Wiggle
noting the "Known Issues" section.

--Hiram

Alexander Donath wrote:
> Hi,
> 
> I stumbled across an issue which was already mentioned in the mailing list a 
> few
> years ago and seemed to be solved.
> I've downloaded phastCons values for the multiple alignments of the 
> chromosomes
> of the 6 nematodes via the browser tool and the ftp server
> (http://hgdownload.cse.ucsc.edu/goldenPath/ce6/phastCons6way/). Somehow the
> values for the positions differ, e.g.:
> 
> values from the table tool:
> 
> track type=wiggle_0 name="Conservation" description="Multiz Alignment &
> Conservation (6 nematodes)"
> #       output date: 2008-11-12 16:34:21 UTC
> #       chrom specified: chrI
> #       position specified: 1-10000000
> #       This data has been compressed with a minor loss in resolution.
> #       (Worst case: 0.0078125)  The original source data
> #       (before querying and compression) is available at
> #               http://hgdownload.cse.ucsc.edu/downloads.html
> variableStep chrom=chrI span=1
> 1521    0.208543
> 1522    0.339598
> 1523    0.415472
> 1524    0.601709
> 1525    0.718969
> 1526    0.787945
> 1527    0.822433
> 1528    0.829331
> 1529    0.822433
> 1530    0.787945
> 
> values from the chrI.data.gz file from the ftp directory:
> 
> fixedStep chrom=chrI start=1521 step=1
> 0.215
> 0.345
> 0.419
> 0.604
> 0.720
> 0.793
> 0.823
> 0.833
> 0.827
> 0.789
> 
> 
> How is that possible? And which values are correct?
> 
> Best,
> Alex
> 

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