I am concerned that there has been a duplication of chromosome 4 material in the current annotation (as well as in the last annotation). Our lab works on genes involved in tooth development, such as ENAM and AMBN. In aligning ENAM sequences to the current UCSC annotation, I got a perfect match to ENAM, but also a perfect match to a region between AMBN and ENAM. I hadn't noticed this before. I BLATed chunks of the ENAM genomic sequence (1900, 2500, even over 7000 bp) and got an EXACT match to the region in between AMBN and ENAM. This seems peculiar to me. Could you please check this for me? Thanks.
Suzanne Hart NHGRI _______________________________________________ Genome maillist - [email protected] http://www.soe.ucsc.edu/mailman/listinfo/genome
