What I really want to know what I need to do to get the listed alleles  
to be oriented on the fwd/+ strand?

Do you internally align the dbSNP fasta sequences to the hg18 to  
ascertain the "strand" or are these records straight copies from dbSNP?

Thanks!
Paul


On Mar 22, 2009, at 11:51 AM, Paul de Bakker wrote:

> Hi [email protected]
>
> I have downloaded the dbSNP129 data from the Table browser  
> (database: hg18) and I wanted to check with you that the listed  
> "strand" field refers to the + or - strand of the genome assembly  
> (i.e. hg18)?     That is, if I make everything on the + strand I  
> only need to flip the Watson-Crick bases for the SNPs where strand =  
> "-"?
>
> Thanks
> Paul
>

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