Hi Kayla,

I was able to convert some wig files into the bigWig format and display 
the tracks in the UCSC genome browser. However, during the conversion from 
wig to bigWig format, I noticed that "wigToBigWig" consumes a lot of 
memory. For example, to convert a ~10 Gb wig file, it maxed out our server 
with 32 Gb memory and used >10 Gb of swap space as well. This make the 
conversion runs quite slowly (~10 hr). Do you have any suggestions as to 
how to make this process more memory efficient?

Thanks!

-Wei





Kayla Smith <[email protected]> 
05/20/2009 04:56 PM

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[email protected]
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[email protected]
Subject
Re: [Genome] wigToBigWig and bedToBigBed







Hello Wei,

Thank you for your interest in our new bigBed and bigWig formats.  While 
we have not formally released these utilities, we have made them available 
here:

This first cut of the executables is here:
http://genome-test.cse.ucsc.edu/admin/exe/linux.x86_64/
with README files such as the following:
        
http://genome-test.cse.ucsc.edu/admin/exe/linux.x86_64/bigBedWigs.txt

Please let us know if you experience any difficulties.

Kayla Smith
UCSC Genome Bioinformatics Group


----- [email protected] wrote:

> Hi,
> 
> I am interested in the new bigwig and bigbed formats. Could you please
> 
> point me to the download site of wigToBigWig and bedToBigBed? Thanks a
> 
> lot!
> 
> -Wei Tao, PhD.
> Bioinformatics
> Agencourt Bioscience
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