Hello:

I have been looking for a tool that can compare two lists of multi- 
block genomic features (or genome alignments in PSL, e.g.) and output  
the list of features that overlap. I have found the intersectBed (BED  
format) and the fjoin (GFF format) programs, which do this but in a  
one block basis, i.e. they intersect one block or exon at a time,  
regardless of wether other blocks also match or not.

I am interested in annotating microarray probes with genes and  
transcripts. If a probe align to the genome say, in two blocks  
separated by a gap, this probe should be annotated to a transcript  
only if both blocks match (overlap) two consecutive exons in a  
transcript.

I would like to know if you have any program that can do this before I  
decide if I should write my own.

Thank you in advance,

Ricardo Verdugo


~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
Ricardo A. Verdugo S., D.V.M. Ph.D.
Postdoctoral Fellow
Gary Churchill Group
The Jackson Laboratory
600 Main Street,
Bar Harbor, ME 04609
[email protected]
+1-207-288-6715
+1-207-288-6847 Fax
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

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