Hi Alex, The Genome Reference Consortium (GRC) shows chr1 as being 249,250,621 bp (http://www.ncbi.nlm.nih.gov/projects/genome/assembly/grc/human/data/index.shtml#), the same as what is displayed here at UCSC. The phenomena you describe between hs_ref_GRCh37_chr1.fa and the UCSC genome is due to telomeres at the beginning of the chromosome.
I hope this information is helpful. Please feel free to contact the mail list again if you require further assistance. Best, Mary ------------------ Mary Goldman UCSC Bioinformatics Group On 11/9/10 9:32 AM, guoshicheng2005 wrote: > Dear sir: > I want to know why the UCSC hg19 Genome is exactly same as the GRCh37 > data. > for example: > 1. The size of the chr1 is 230176483 in NCBI GRCh37 Chr1 but 249,250,621 > in UCSC hg19 > 2. The first base of NCBI human Genome hs_ref_GRCh37_chr1.fa locate to > 10001 in UCSC hg19 > > Looking forward for you help,Your swift reply will be great appreciated. > yours Alex > 10th Nov 2010 > > > > -- > > Cancer Epigenetics and Gene Therapy Program, > The State-key Laboratory for Oncogenes and Relatead Genes, > Shanghai Cancer Institute, > Shanghai Jiaotong University, > LN 2200/25, Xietu Road, > Shanghai 200032, China > _______________________________________________ > Genome maillist - [email protected] > https://lists.soe.ucsc.edu/mailman/listinfo/genome > _______________________________________________ Genome maillist - [email protected] https://lists.soe.ucsc.edu/mailman/listinfo/genome
