Good Afternoon Jiannan:

Thank you for this example.  This triggers a problem in the liftOver program.
The correction to the source tree will filter out to our public GIT source
server in a few hours.

--Hiram

jiannan lin wrote:
> Dear UCSC Administrator:
>        I  occur to one problem when using Liftover. I try to Liftover human
> hg19 to rhesus RheMac2 with the strand info.
> The human test data:
> chr17 20786657 20786661 humantest 100 +
> After Liftovering to RheMac2 (-multiple), the result is:
> chr16 19897426 19897428 humantest 1 -
> chr16 19897421 19897423 humantest 2 +
> 
> But  I split the human data (chr17 20786657 20786661) into:
> chr17 20786657 20786659 humantest11 100 +
> chr17 20786659 20786661 humantest22 100 +
> The Liftovering result is
> chr16 19897426 19897428 humantest11 1 -
> chr16 19897421 19897423 humantest22 1 -
> what is the reason for the strand difference of the two Liftover running?
> The second Liftover running is consistent with the hg19-RheMac2 net
> alignment .
>    Thanks very much!
> Best Wishes!
> Jiannan
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