Good Afternoon David: The wigToBigWig program will consume some 10s of Gb of memory as it works. It is perfectly normal for it to grow very large in memory while it works.
If you broke up your data into individual files for each chrom, you would end up with individual tracks for each chrom. You could kinda get that to work with a lot of tracks like that, but it would be inconvenient. If you can find a larger memory machine, you could get the encoding accomplished. --Hiram David Goode wrote: > I have a wig file that contains one entry for each site in hg19. Perhaps > not surprisingly, when I try to convert it to a bigWig file using > wigToBigWig, I get a malloc error. > > Could I instead make a wig for each chromosome and convert each wig to a > bigWig? Is it okay to concatenate multiple bigWig files like this? > > Thanks! > > David _______________________________________________ Genome maillist - [email protected] https://lists.soe.ucsc.edu/mailman/listinfo/genome
