Dear Hiram,

thank you for your quick response and your kind offer to help.

I just noticed in the bigWigInfo output that the latest binary files I 
obtained from the UCSC website still produce bigWig version 3 files.
It seems that might be problematic: 
https://lists.soe.ucsc.edu/pipermail/genome/2010-October/023674.html
I have now built the binaries from source to create bigwig version 4 
files instead. The new bigwig files work ! So I guess my problems may 
have been caused by issues with the bigwig version 3 format. Does that 
sound reasonable ?

Cheers,
Thomas


Hiram Clawson wrote:
> Good Afternoon Thomas:
>
> This could certainly be a bug in the system.
> Can you supply a URL to your bedGraph and chrom.sizes file ?
> You can send that to me privately:  hiram at soe dot ucsc dot edu
>
> --Hiram
>
> Thomas Sandmann wrote:
>> Dear UCSC genome browser team,
>>
>> I am working with a large bedGraph file (800 Mb), which I would like 
>> to convert to bigWig format for display in a local browser. The data 
>> is from a non-model organism with a large number of supercontigs as 
>> chromosomes (>40.000). Unfortunately, when I try to extract data for 
>> different chromosomes, I only get results for the first two 
>> chromsomes (v31.000000, v31.000001) but nothing for any of the other 
>> chromosomes (see below).
>>
>> I have performed the following steps in a ubuntu Linux environment, 
>> using binary files from the UCSC genome browser server 
>> <http://hgdownload.cse.ucsc.edu/admin/exe/linux.x86_64/> that carry 
>> the date 14-Dec-2010. 

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