Good Afternoon Archie: You are correct, there are many sources of information on this subject.
Depending upon the area of the evolutionary tree you might be working on, you can go to your species of particular interest in the genome browser to see if it has a "Conservation" track. Each of these conservation tracks on each browser is based on alignments from other species to that specific species as the "reference" sequence. Some of the conservation tracks have several sub-groups of species. Some of the newer conservation tracks have two different types of prediction algorithms on display, from the phastCons and phyloP programs. The human sequence hg19 has the largest set of species in the measurements: http://genome.ucsc.edu/cgi-bin/hgTrackUi?db=hg19&g=cons46way You will want to read about the difference of phastCons and phyloP to decide which might be best for your project. --Hiram Archie Russell wrote: > I'm looking for a simple source of base-by-base conservation info in human. > Is there a file(s) I could download that has this sort of thing or is all > the info on longer blocks? > I see so many tracks, not sure where to start. _______________________________________________ Genome maillist - [email protected] https://lists.soe.ucsc.edu/mailman/listinfo/genome
