Hi Jose, To find how one nucleotide change (also known as Single Nucleotide Polymorphism, SNP) in one gene affects the protein sequence go to the genome browser and click on the description page for "SNPs (131)" track. Here is a link to the track description for the hg19 assembly: http://genome.ucsc.edu/cgi-bin/hgTrackUi?db=hg19&g=snp131
The description has information to help you with the track control settings. Hope this helps! If you have further questions, please contact the mailing list again. Vanessa Kirkup Swing UCSC Genome Bioinformatics Group ----- Original Message ----- From: "Josué Vázquez" <[email protected]> To: [email protected] Sent: Thursday, March 17, 2011 7:34:46 AM Subject: [Genome] another doubts. hello again: Sorry if I bother to much, but I need to learn how to use this browser and I need also finish some problems with it. I would like to know this things: How Can I find the effect of one nucleotide change in one gen (let say UMOD), on protein sequence How I will know wich exon this change is, and what would be the designation of the variant. Thanks alot -- *Josué Iván Vázquez Corona* *Ústav dědičných metabolických poruch VFN a 1. LF UK Praha* *Institute of Inherited Metabolic Disorders, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague* _______________________________________________ Genome maillist - [email protected] https://lists.soe.ucsc.edu/mailman/listinfo/genome _______________________________________________ Genome maillist - [email protected] https://lists.soe.ucsc.edu/mailman/listinfo/genome
