Hi Huang-Wen,

That is our representation for insertions into the reference genome. The 
length of the item is 0 in the reference genome, and greater than 0 for 
the insertion alleles.

In our internal 0-based, half-open coordinate system, start is equal to 
end when length is 0 (chr1 10433 10433). To convert our internal 
coordinates to the 1-based, fully-closed coords that everyone expects, 
we add 1 to the start position, so that becomes the chr1:10434-10433 
that you see in the browser. It looks odd, but the usual 1-based length 
calculation (end - start + 1) works out to 0.

For more information on our 0-based, half-open coordinate system, please 
see this FAQ: http://genome.ucsc.edu/FAQ/FAQtracks.html#tracks1.
Please don't hesitate to contact the mail list again if you have any 
further questions.

Katrina Learned
UCSC Genome Bioinformatics Group

Huang-Wen Chen wrote, On 3/18/2011 10:54 AM:
> Hi,
>
> snp131 contains ~10% of records with a property that the start position
> is greater than the end position. For example, we saw
> "Position: chr1:10434-10433" for rs56289060. The regions they described
> are correct according to dbSNP, except that the start and end position
> are reversed (this happens even on the sense strand). Is there any
> special reason for this reverse representation of regions ? Or, any plan
> to swap them such that chromStart<  chromEnd holds for consistency ?
> Thanks ..
>
> ----
> Huang-Wen (Howard) Chen, Ph.D.
> Email: [email protected]
> Phone: (215) 503-6151
>
> Computational Medicine Center
> Jefferson Medical College
> Thomas Jefferson University
> http://cm.jefferson.edu
>
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