On Tue, May 31, 2011 at 4:11 PM, Brooke Rhead <[email protected]> wrote:
> Hi Anoma,
>
> Run the liftOver command without arguments to see the usage statement.
> The correct command line is:
>
>    liftOver oldFile map.chain newFile unMapped
>
> (In addition to the newFile, you need to include a file for unmapped
> regions.)  Also, you will need to use the "-gff" option, since your
> input file is in .gff format.  So your command line should look like:
>
>    liftOver -gff oldFile hg18ToHg19.over.chain newFile unMapped
>
> Note that the liftOver tool will not necessarily get you the same
> mappings in hg19 that appear in the build 132 SNP tracks.
>
> I hope this is helpful.  If you have further questions, please feel free
> to contact us again at [email protected].
>
> --
> Brooke Rhead
> UCSC Genome Bioinformatics Group
>
>
>
> On 05/30/11 09:22, Anoma Jaya wrote:
>> Hi,
>>
>> I want to convert coordinates of SNPs filtered using hg18 to coordinates of
>> hg19 with liftOver. I got input data files
>> from http://hgdownload.cse.ucsc.edu/goldenPath/hg18/liftOver/ link.
>> Can U please tell me what is the command line that I should give in the Linux
>> terminal to execute the task?
>>
>> ( I gave
>>           $ liftOver oldFile hg18ToHg19.over.chain newFile
>>
>> oldFile = file with coordinates of the SNPs
>> newFile = output file,)
>>
>> But this did not work.
>>
>> My oldFile was a .gff file as follows,
>>
>> Chrm    Coordi  alli            old rs
>>
>> chr10 56397   C       CT      rs12262442      28      C/T     17      11
>> chr10 61776   T       CT      rs61838967      15      T/C     7       8
>>

Also, this doesn't appear to be gff, looks more like VCF.


>> Was there a problem with my command line or with my .gff file ? ( or with 
>> both ?)
>>
>> Waiting for an early reply,
>>
>> Thank you very much.
>>
>> Anoma
>>
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