Hi Mark, Sorry for the delay in getting back to you. For a general overview of how to use the Genome Browser, see the resources on this page:
http://genome.ucsc.edu/training.html Open Helix provides free online tutorials that provide a quick start to using the Browser: http://www.openhelix.com/downloads/ucsc/ucsc_home.shtml You will likely want to use either the human GRCh37/hg19 assembly, which is the latest human assembly, or the NCBI36/hg18 assembly, which is older but is populated with more annotation tracks. I recommend searching for the data you are interested in on both assemblies. To view the region around a particular gene, type the gene name in the "gene" box and hit submit/jump. To find tracks that contain methylation data, you can either scroll down the page and browse tracks by clicking on the blue track names and reading the descriptions to see if they are what you need (look in the "Regulation" group), or you can hit the "track search" button, enter some search terms, and read track descriptions and select tracks to display. One of our engineers recommends using the "HAIB Methyl27" track, available on the NCBI36/hg18 assembly. I hope this helps get you started. If you have further questions, please write back to [email protected]. -- Brooke Rhead UCSC Genome Bioinformatics Group On 06/15/11 09:50, Fang, Yanchu wrote: > Dear Sir, > > > > I am not familiar with your database. > http://genome.ucsc.edu/cgi-bin/hgGateway > > > > Would you be so kind to show me (steps) how to search gene methylation > from your data base? Suppose I am interested in looking at the DNA > methylation sites in promoter region or the DNA sequences between exons > for EGF gene via your database (website). How can I do that? > > > > Many thanks! > > Regards > > Mark > > > > _______________________________________________ > Genome maillist - [email protected] > https://lists.soe.ucsc.edu/mailman/listinfo/genome _______________________________________________ Genome maillist - [email protected] https://lists.soe.ucsc.edu/mailman/listinfo/genome
